Anti-Aging drug and football drills join forces to fight brittle bones
NCT ID NCT06789900
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a weekly dose of everolimus (a drug that targets aging pathways) and/or a fun exercise program called 'Football Fitness' can prevent the rapid bone loss that happens after menopause. 136 healthy women aged 45-60 will be assigned to one of four groups: exercise only, drug only, both, or general health advice. The main goal is to see if these interventions improve bone formation markers after 24 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Everolimus (a rapamycin analog) and/or structured exercise training
What this could lead to
If successful, this could point toward a drug-and-exercise strategy to prevent postmenopausal bone loss and reduce fracture risk.
What could go wrong
This is a small, early-phase trial (136 women) testing bone marker changes, not fractures. Everolimus is an immunosuppressant with side effects, and benefits may not translate to real-world fracture prevention.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Odense University Hospital
Odense, 5000, Denmark