Which cervical prep eases hysteroscopy for postmenopausal women?
NCT ID NCT07697781
First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time
Summary
This trial tests whether preparing the cervix with medication before office hysteroscopy helps postmenopausal women have a more successful and less painful procedure. Participants are randomly assigned to receive either oral misoprostol, vaginal estrogen for 7 or 14 days, or no preparation at all. The study measures how often the hysteroscopy is completed successfully and how much pain women report during and after the procedure. The goal is to find the best way to make this common diagnostic exam more comfortable and effective for older women.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- misoprostol and vaginal estrogen
- What this could lead to
- If one preparation method works best, it could make office hysteroscopy easier and less painful for postmenopausal women, improving diagnosis of uterine conditions.
- What could go wrong
- This is a small, early-stage trial with 120 participants, so results may not apply to all women. The preparations themselves may cause side effects like cramping or irritation.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Maternity and neonatology center of Tunis
RECRUITINGTunis, Tunis Governorate, 1007, Tunisia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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