Can a reusable device match the standard for uterine biopsy?

NCT ID NCT07745595

First seen Aug 04, 2026 · Last updated Aug 13, 2026 · Updated 3 times

Summary

This trial compares two outpatient methods for sampling the lining of the uterus in women with abnormal uterine bleeding. The standard method uses a single-use Pipelle device, while the alternative uses a reusable manual vacuum aspiration (MVA) cannula, which is cheaper and requires no electricity. The study will see if the MVA device provides tissue samples that are just as good for diagnosing conditions like hyperplasia or cancer. If it works, it could offer a more affordable option for diagnosis in low-resource settings.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Manual Vacuum Aspiration (MVA) cannula compared to Pipelle endometrial suction curette
What this could lead to
If MVA proves as effective as Pipelle, it could offer a cheaper, reusable option for diagnosing uterine conditions, especially in low-resource settings.
What could go wrong
This is a small, early-stage comparison. The MVA device may not match the diagnostic accuracy of the standard Pipelle, and results may not apply to all populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Obstetric Labor, Premature Premature Birth

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

More trials for these conditions

Other studies related to the condition(s) this trial covers.