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Could a higher steroid dose help preterm babies breathe easier?

NCT ID NCT07765329

Completed Disease control Sponsor: Stella Maris Women and Children Hospital Source: ClinicalTrials.gov ↗

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This study looks at whether a higher dose of dexamethasone, a steroid given to pregnant women at risk of early birth, helps preterm babies' lungs mature better. Researchers are comparing babies born between 26 and 36 weeks whose mothers received either 12 mg or 6 mg of dexamethasone every 12 hours. They want to see if the higher dose reduces the need for breathing support and shortens NICU stays, while also checking safety for both mothers and babies.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Dexamethasone (antenatal corticosteroid) given to pregnant women at risk of preterm birth
What this could lead to
If the higher dose works better, it could shorten breathing support and NICU stays for preterm babies, improving their early health.
What could go wrong
This is an observational review of past records, not a controlled experiment, so results may be influenced by other factors. The higher dose may also carry risks for mothers or babies.

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Conditions

The condition(s) this trial relates to.

adult acute respiratory distress syndrome necrotizing enterocolitis neonatal sepsis newborn respiratory distress syndrome Premature Birth respiratory distress syndrome in premature infants Respiratory Distress Syndrome, Newborn

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRAVENTRICULAR HEMORRHAGE (IVH) INTRAVENTRICULAR HEMORRHAGE NEONATAL MATERNAL INFECTION DURING PREGNANCY NECROTIZING ENTEROCOLITIS (NEC) NEONATAL HYPOGLYCEMIA NEONATAL RESPIRATORY DISTRESS SYNDROME NEONATAL SEPSIS NEURODEVELOPMENTAL DISORDER OF FOETUS PREMATURE BIRTH RESPIRATORY DISTRESS SYNDROME (RDS)

Contacts and locations

Locations

  • RSIA Stella Maris

    Medan, North Sumatera, 20152, Indonesia

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