PREMATURE BIRTH

This study is testing whether using an air purifier in the home can help improve lung development in babies who were born prematurely. Researchers will measure air quality and track the health of about 180 infants, aged 0-6 years, who were born before 37 weeks. The goal is to see…

This study is testing whether a single, lower dose of a steroid medicine is just as safe and effective as the standard two-dose treatment for pregnant people at risk of delivering their baby too early. The medicine helps speed up the baby's lung development before birth. Research…

This study is testing if a lung medication called surfactant, given using a gentler method that doesn't require a breathing machine, can help more premature babies survive breathing problems in African hospitals. It will involve over 1,500 premature infants with breathing difficu…

This study is testing if adding a second antibiotic (azithromycin) to the standard treatment (ampicillin) leads to healthier babies when a pregnant person's water breaks too early, between 34 and 37 weeks. Researchers will compare the two treatments in about 311 participants to s…

This study is testing a new medical device designed to help preterm infants in the hospital develop better speech sound processing. The device is a special pacifier that plays recordings of the baby's mother's voice when the baby sucks on it. Researchers will measure brain activi…

This study is testing a two-part program to help premature babies in the hospital learn to feed by mouth. It combines gentle mouth exercises with a special feeding schedule based on the time of day. Researchers want to see if this helps babies become ready to feed, switch to full…

This study is testing a new type of camera called a Mueller polarimetric colposcope to see if it can predict when a pregnant person will give birth. Researchers want to see if images of the cervix can create a 'score' that accurately forecasts delivery date and identifies risk of…

This study tests whether a virtual early learning program can help babies (ages 0-5) who experienced oxygen deprivation at birth or were born very prematurely. Researchers want to see if online sessions are as effective as in-person therapy at improving children's thinking, movem…

This study is testing whether a gentle, tingling electrical stimulation on a baby's ear, given during breastfeeding, can help them learn the feeding skills of latching, sucking, and swallowing more effectively. It will involve 10 premature or sick term infants in the NICU who are…

This study is testing whether providing extra support from doulas (trained birth companions) and care coordinators helps parents of very premature babies. It focuses on parents in a Philadelphia hospital NICU, aiming to reduce stress, anxiety, and depression after their baby goes…

This study aims to understand how being born moderately premature affects how a baby's brain processes speech sounds. Researchers will track 160 infants—some born premature, some full-term—using brain wave measurements (EEG) as they listen to syllables. The goal is to identify ea…

This study aims to improve how doctors counsel families facing the possibility of an extremely premature birth. Researchers will first interview families to learn their preferred language and then use that information to create new training programs for doctors. The goal is to he…

This research aims to understand how air pollution affects pregnancy. Scientists will use artificial intelligence to analyze the health records of 18,000 women who gave birth in London, linking them to local air quality data. The goal is to build a computer model that can predict…

This study aims to collect health data and biological samples from 1300 very premature babies over several years. Researchers want to identify factors that help or harm development in areas like brain function, vision, hearing, and organ health. The goal is to build a research re…

This study aims to understand how to spot early signs of future thinking and attention problems in babies who had a brain injury around birth. Researchers will observe 100 infants, some healthy and some with a history of brain injury, by watching them play simple games, measuring…

This study creates a registry to collect information on the care and outcomes of extremely premature babies born at 22-23 weeks of pregnancy. It involves up to 5,000 mothers and infants from multiple hospitals. The goal is to gather data on treatments and results to help hospital…

This study is creating a large registry to collect information from 3,000 women who experienced their water breaking too early in pregnancy (before 37 weeks). The goal is to understand what causes this complication, track how doctors manage these pregnancies, and learn about the …

This study is testing a decision support tool designed to help parents facing the threat of an extremely premature birth (between 22 and 25 weeks). The tool provides information and helps clarify values about difficult care choices for the newborn. Researchers are comparing paren…