PREMATURE BIRTH
Clinical trials for PREMATURE BIRTH explained in plain language.
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Plastic bag beats blanket for preemie warmth?
Disease control CompletedThis study tested whether wrapping premature babies in a plastic bag (polyethylene bag) keeps them warmer than the usual prewarmed blanket during transfer from the delivery room to the NICU. Sixty-seven babies weighing 2 kilograms or less were randomly assigned to one of the two …
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Mario Adrián Tienda Vázquez • Aim: Disease control
Last updated Jun 27, 2026 14:01 UTC
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Simple CPAP right after birth may keep late preterm babies out of the NICU
Disease control CompletedThis pilot study tested whether giving late preterm babies (34-37 weeks) born by C-section a short course of CPAP breathing support right after delivery could reduce their need for extra oxygen or breathing help. 120 babies were randomly assigned to receive either early CPAP or s…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: University of Oklahoma • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Skin-to-Skin care may boost survival in tiny newborns
Disease control CompletedThis study looked at whether starting kangaroo mother care (skin-to-skin contact and breastfeeding support) within the first 24 hours helps healthy preterm babies born weighing less than 2000 grams. 100 infants were randomly assigned to early kangaroo care or standard care. The r…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: University of Health Sciences Lahore • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Group prenatal care shows promise for reducing preterm births in pacific islander community
Prevention CompletedThis study tested whether a group-based prenatal program called Centering Pregnancy, combined with a care navigator, could improve pregnancy outcomes for Marshallese women. 38 pregnant women participated, and researchers tracked preterm birth, low birthweight, and C-section rates…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: University of Arkansas • Aim: Prevention
Last updated Jun 27, 2026 12:06 UTC
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Progesterone or pessary: which prevents preterm birth better?
Prevention CompletedThis study tested whether natural progesterone or a cervical pessary (a silicone ring placed in the vagina) is better at preventing early birth in pregnant women with a short cervix (25 mm or less). The trial included 203 women with a single baby. Researchers tracked how many gav…
Matched conditions: PREMATURE BIRTH
Phase: PHASE4 • Sponsor: University of Sao Paulo • Aim: Prevention
Last updated Jun 27, 2026 11:02 UTC
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Vaginal gel or shot: which better prevents preterm birth?
Prevention CompletedThis study tested two forms of progesterone—vaginal gel and a shot—to see which works better at preventing another preterm birth in women who had one before. About 210 pregnant women with a prior preterm birth took part. The goal was to find out if the vaginal option is more effe…
Matched conditions: PREMATURE BIRTH
Phase: PHASE4 • Sponsor: Thomas Jefferson University • Aim: Prevention
Last updated Jun 27, 2026 09:08 UTC
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Could music soothe preterm babies and their parents?
Symptom relief CompletedThis study tested music therapy for preterm infants in the NICU. Twenty-one medically stable babies (28 weeks or older) and their caregivers received music therapy sessions, including skin-to-skin contact, singing, and support. Researchers measured heart rate, breathing, temperat…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Anglia Ruskin University • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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VR headsets may boost breast milk in preemie moms
Symptom relief CompletedThis study tested whether using virtual reality (VR) for relaxation helps mothers of premature babies produce more breast milk and feel more confident about breastfeeding. Forty-four first-time mothers with babies in the NICU used a VR headset showing calming nature scenes and mu…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Kocaeli University • Aim: Symptom relief
Last updated Jun 27, 2026 08:10 UTC
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Tiny brains, big insights: how premature infants' brain waves reveal early development
Knowledge-focused CompletedThis study looked at brain wave patterns in 28 healthy premature infants born between 26 and 32 weeks of pregnancy. Researchers used EEG to measure a specific type of brain activity called temporal theta slow-wave activity. The goal was to understand where this activity comes fro…
Matched conditions: PREMATURE BIRTH
Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Premature baby breathing study completed: what works best?
Knowledge-focused CompletedThis study looked at 136 premature babies who needed breathing help. Researchers tracked how long they needed support and checked for lung problems. The goal was to learn more about different non-invasive breathing methods, not to test a new treatment.
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Breast milk showdown: does pasteurization weaken gut benefits for preemies?
Knowledge-focused CompletedThis study looked at 55 very premature babies (born at 28-30 weeks) to see if natural mother's milk or pasteurized milk better helps their guts mature. Researchers measured bioactive molecules in the milk and tracked gut development during small feedings. The goal was to understa…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Mom's voice may boost preemie brain growth
Knowledge-focused CompletedThis study tested whether playing recordings of a mother's voice to preterm babies in the NICU helps their brain and language development. Researchers enrolled 57 preterm infants born between 24 and 31 weeks. The goal was to see if this simple, non-invasive intervention could imp…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Can a web program help parents of preemie toddlers?
Knowledge-focused CompletedThis study tested a web-based parent training program called ezParent, with or without extra telephone coaching, for parents of toddlers born very premature (before 32 weeks). Over 450 parents took part, and researchers measured changes in parenting skills, stress, and child beha…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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New feeding method aims to protect premature Babies' lungs
Knowledge-focused CompletedThis study looked at whether feeding very low birth weight premature infants directly into the duodenum (the first part of the small intestine) is safe and doable. The goal is to reduce stomach reflux that can worsen lung damage. Twenty-four infants were randomly assigned to rece…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Johns Hopkins All Children's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Light device could spot brain trouble in tiniest newborns
Knowledge-focused CompletedThis study tested a new, noninvasive device that uses light to monitor blood flow and oxygen in the brains of extremely premature babies. Researchers followed 100 infants born before 29 weeks to see if the device could detect problems linked to brain bleeding. The goal is to give…
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: Maria Angela Franceschini • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:04 UTC
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Parents' syringe feeding may boost NICU presence for preemies
Knowledge-focused CompletedThis study looked at whether allowing parents to push a syringe for their premature baby's tube feeding (instead of using a machine) helps them spend more time in the neonatal intensive care unit. 72 babies born between 30 and 34 weeks were included. The main goal was to compare …
Matched conditions: PREMATURE BIRTH
Phase: NA • Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:58 UTC
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Car seat breathing risk for preemies measured in new study
Knowledge-focused CompletedThis study looked at 51 stable premature infants to see how their lung volume changes when placed in a car seat. Using a special imaging technique called electrical impedance tomography, researchers measured breathing patterns in three positions: lying flat, sitting in a car seat…
Matched conditions: PREMATURE BIRTH
Sponsor: University of Zurich • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC
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Study links vaginal germs to preterm birth risk
Knowledge-focused CompletedThis study followed 603 pregnant women in South Africa to see if infections or bacteria in the vagina are linked to how early they give birth. Researchers tested for sexually transmitted infections, yeast, and other germs at the start of pregnancy and again at 30-34 weeks. The go…
Matched conditions: PREMATURE BIRTH
Sponsor: University of Bern • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:35 UTC
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Massive study reveals why preterm babies stay in hospital too long
Knowledge-focused CompletedThis study looked at medical records of 250,000 preterm infants born in England and Wales to find out when they are ready to go home. Researchers tracked three key milestones: breathing without help, feeding by mouth, and reaching a healthy weight. The goal is to reduce unnecessa…
Matched conditions: PREMATURE BIRTH
Sponsor: University Hospitals of Derby and Burton NHS Foundation Trust • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:35 UTC