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Study links vaginal germs to preterm birth risk

NCT ID NCT06131749

Completed Knowledge-focused Sponsor: University of Bern Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study followed 603 pregnant women in South Africa to see if infections or bacteria in the vagina are linked to how early they give birth. Researchers tested for sexually transmitted infections, yeast, and other germs at the start of pregnancy and again at 30-34 weeks. The goal was to understand which combinations of microorganisms might lead to earlier delivery. The study is complete and may help design future ways to prevent preterm birth.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could help identify which infections or bacteria combinations increase the risk of early birth, leading to better screening and prevention strategies.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Results may not apply to other populations or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bacterial vaginosis chlamydia trachomatis infectious disease gonorrhea hepatitis HIV infectious disease infectious disease Mycoplasmoides infection Pregnancy Complications, Infectious Premature Birth sexually transmitted disease Trichomonas vaginitis urogenital infection trichomoniasis Ureaplasma urethritis vulvovaginal candidiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BACTERIAL VAGINOSIS CHLAMYDIA TRACHOMATIS INFECTION GENITAL MYCOPLASMA INFECTION HIV INFECTIONS MICROBIAL COLONIZATION MYCOPLASMA GENITALIUM INFECTION NEISSERIA GONORRHEAE INFECTION PREGNANCY; INFECTION PREMATURE BIRTH SEXUALLY TRANSMITTED INFECTIONS (NOT HIV OR HEPATITIS) TRICHOMONAS VAGINITIS UREAPLASMA UREALYTICUM INFECTION VAGINAL CANDIDA

Contacts and locations

Locations

  • Empilweni Gompo Community Health Centre

    East London, Eastern Cape, 5209, South Africa

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