University Of Bern

This study tests a new collagen material against the standard gum graft surgery for treating gum recession in people who had braces. About 60 healthy adults will receive one of the two treatments to cover exposed tooth roots and thicken gum tissue. The goal is to see if the new m…

This study tests whether adding platelet-rich fibrin (PRF) — a concentrate from the patient's own blood — to standard implant surgery improves healing of bone and gum damage around dental implants. Forty adults with peri-implantitis (infection and bone loss around implants) will …

This study is testing whether a chewing gum containing special fibers (GOS) can help overweight adults lose weight and improve their metabolism. About 120 adults aged 25 and older with a BMI over 25 will chew the gum regularly. Researchers will measure changes in BMI, blood press…

This study tests a program to help doctors reduce or stop unnecessary prescriptions of acid reflux medications (proton pump inhibitors) in 400 adults in Switzerland. Participants must be 18 or older, taking a daily dose for at least 8 weeks, and have no clear medical need for it.…

This study tests a new smartphone-based system that automatically adjusts insulin delivery for people with type 1 diabetes. Six adults who already use insulin pumps will try the system for a short time under close supervision. The goal is to see if the technology works reliably a…

This study looks at 100 adults who need a lower first molar removed and replaced with a dental implant. The implant is placed 12-16 weeks after extraction, and then a crown is attached either right away or 4 weeks later. Researchers want to see if immediate or early loading leads…

This study tests whether a collagen matrix can help regrow bone and tissue damaged by gum disease as well as a standard bone graft. About 80 adults with advanced gum disease and deep bone defects will receive one of the two treatments during surgery. Researchers will measure chan…

This study is for adults with type 1 diabetes who already use an automated insulin delivery system. Researchers want to see if adding a weekly injection of tirzepatide (a drug that helps control blood sugar and weight) can improve glucose levels even more. About 42 people will ta…

This study tests a new type of dental bridge called the T-bridge, which uses just one implant to replace three missing back teeth. About 50 adults with a 21-24 mm gap will receive the bridge and be followed to see how well the implant and bridge hold up over time. The goal is to …

This study tests whether a modified ketogenic diet (a low-carb, high-fat diet) can help people with alcohol use disorder drink less. Researchers will track 50 participants' adherence to the diet and measure changes in alcohol consumption and cravings. The goal is to see if this d…

This study compares two surgical methods to improve soft tissue volume where a dental bridge will be placed. One method uses a piece of the patient's own gum tissue, the other uses a collagen material. The goal is to see which approach gives better long-lasting shape and volume, …

This study tests a one-hour online program called UKADO for people waiting to start face-to-face therapy for anxiety or depression. About 312 adults will try different versions of the program to see which works best. The goal is to find a way to help people feel better while they…

This study tests whether applying a cross-linked hyaluronic acid gel during root-end surgery helps gums heal faster and lowers pain. About 46 adults with a tooth infection that didn't resolve after standard root canal treatment will take part. Half will get the gel during surgery…

This study tests a simple, non-invasive device that plays soft sounds during sleep to boost deep sleep and improve memory. Sixty older adults with mild memory problems will use the device at home for four weeks. Researchers will measure memory, brain activity, and blood markers t…

This study tests whether adding antidepressant medication to the Friendship Bench talk therapy works better than therapy alone for adults with moderate to severe depression in Zimbabwe. About 296 people will take part, and researchers will measure improvement using a standard dep…

This study follows 3,000 childhood cancer survivors in Switzerland to understand long-term health problems caused by past cancer treatments. Participants undergo regular check-ups, lab tests, and questionnaires as part of their normal follow-up care. The goal is to better detect …

This study measures chemicals in the breath of 60 adults (with type 1 diabetes, type 2 diabetes, or no diabetes) throughout the day. The goal is to see if these breath patterns change with time and blood sugar levels. No treatment is given; it is purely observational to learn mor…

This study looks at how the brain works in people who have attempted suicide, those who have only thought about it, and two control groups. Researchers will use computer tasks to measure attention, impulse control, and other thinking skills. The goal is to find patterns that migh…

This study tests whether sensors inside a car can tell when a driver is impaired by cannabis. About 45 healthy adults who regularly use cannabis will drive on a closed track after consuming cannabis, while sensors record their driving, eye movements, and body signals. The goal is…

This study is a registry that collects health information from children and adults in Switzerland who have neuromuscular disorders like SMA, Duchenne, and Becker muscular dystrophy. It does not test a new treatment but gathers data on symptoms, treatments, and quality of life ove…

This study follows 1000 people with Primary Ciliary Dyskinesia (PCD) for two years to see how their ear, nose, and throat symptoms change over time. Researchers will collect information during regular clinic visits to better understand the course of the disease. No new treatments…

This study is creating a national registry in Switzerland for people diagnosed with Primary Ciliary Dyskinesia (PCD), a rare lung condition. Researchers will collect information on symptoms, treatments, and test results from up to 800 participants over time. The goal is to better…

This study looks at how everyday physical activities, like walking to the store or doing chores, affect energy levels and mood in people with depression. Researchers will use activity trackers and electronic diaries to collect real-time data from 180 participants. The goal is to …

This study looks at people who have long-lasting health problems after getting the COVID-19 vaccine, a condition called Post-Acute COVID-19 Vaccination Syndrome (PACVS). Researchers will track symptoms like fatigue and brain fog over eight months and test blood and blood vessel f…

This study follows 6,000 children in Switzerland who have breathing issues like wheezing, coughing, or trouble breathing during exercise. Researchers collect information from doctor visits and family questionnaires to learn more about these problems and how to diagnose and treat …

This study follows 250 women living with HIV in Zimbabwe who have been treated for cervical pre-cancer. Researchers want to understand why some women's pre-cancer returns after treatment and how to better monitor them. Participants will have regular check-ups and tests over two y…

This study is building a national database of people with cerebral palsy (CP) in Switzerland. Researchers will collect information on diagnosis, treatments, and daily life from up to 15,000 participants. The goal is to use this data to improve care and quality of life for childre…

This study looks at how a short therapy program called ASSIP affects thinking and behavior in adults who have attempted suicide. Participants are randomly assigned to receive ASSIP or standard care plus a resource interview. Researchers measure changes in impulse control and othe…

This study is building a national registry for people of any age in Switzerland who have a rare disease or are strongly suspected of having one. The goal is to collect information like diagnosis, symptoms, and genetic data to help researchers understand these diseases better and …

This study is testing whether a smartphone app can help young people aged 14 to 35 with alcohol or cocaine use disorder by training their brain to say "no" to substance-related cues. Participants will use the app for short training sessions over a month, plus booster sessions. Th…

This study tests whether a safe, mild electrical current applied to the scalp can change brain activity and thinking speed in healthy adults. About 196 younger (20-40) and older (60-80) adults will do computer tasks while receiving real or fake stimulation, with brain scans to se…

This study looks at why breast and colorectal cancer survivors may be at higher risk for a common liver condition called MASLD (fatty liver disease). Researchers will use painless scans and blood tests to check for liver damage in 200 survivors. The goal is to find better ways to…

This study follows people with primary ciliary dyskinesia (PCD) worldwide to learn about their symptoms, treatments, and daily life. Participants fill out questionnaires when they join and once a year after that. The goal is to improve health and quality of life for everyone with…