Could a patient's own blood help heal gums? small trial tests PRF as a natural boost to standard periodontitis care
NCT ID NCT07013682
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study tests whether platelet-rich fibrin (PRF) — a concentrate made from a patient's own blood — can improve gum healing after standard deep cleaning for periodontitis. Twenty adults with moderate to severe gum disease will receive deep cleaning on both sides of the mouth, with PRF added to one side. Researchers will measure changes in pocket depths and gum attachment over 6 months to see if PRF offers extra benefit.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
platelet-rich fibrin (PRF)
What this could lead to
If PRF improves gum healing, it could offer a low-cost, natural way to boost standard periodontitis treatment without expensive additives.
What could go wrong
This is a small early-stage trial with only 20 people, so results may not apply widely. PRF may not provide significant benefit over standard care.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Healing of Gum Defects with Hyaluronic Acid & Po NCT06309719
- Periodontal Therapy & Endothelial Dysfunction Tr NCT05906797
- Oral Microbiome Changes in Dental Implant Patien NCT06149585
- Family Oral Bacteria Transmission Study - NCT07674888
- Sterify Gel for Periodontitis: NCT07672665
- MINST vs MIST for Periodontitis: NCT03797807
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Email: •••••@•••••
Locations
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Department of Periodontology, University of Bern
RECRUITINGBern, 3010, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••