Could a patient's own blood help heal gums? small trial tests PRF as a natural boost to standard periodontitis care

NCT ID NCT07013682

Recruiting now Disease control Sponsor: University of Bern Source: ClinicalTrials.gov ↗

First seen Jul 02, 2026 · Last updated Jul 02, 2026

Summary

This study tests whether platelet-rich fibrin (PRF) — a concentrate made from a patient's own blood — can improve gum healing after standard deep cleaning for periodontitis. Twenty adults with moderate to severe gum disease will receive deep cleaning on both sides of the mouth, with PRF added to one side. Researchers will measure changes in pocket depths and gum attachment over 6 months to see if PRF offers extra benefit.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: platelet-rich fibrin (PRF)
What this could lead to: If PRF improves gum healing, it could offer a low-cost, natural way to boost standard periodontitis treatment without expensive additives.
What could go wrong: This is a small early-stage trial with only 20 people, so results may not apply widely. PRF may not provide significant benefit over standard care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Periodontal Attachment Loss periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIODONTAL ATTACHMENT LOSS PERIODONTAL INFLAMMATION PERIODONTITIS

Contacts and locations

Locations

Department of Periodontology, University of Bern
RECRUITING

Bern, 3010, Switzerland

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