Can your own blood help save a failing dental implant?
NCT ID NCT06679283
First seen Apr 08, 2026 · Last updated Jun 23, 2026 · Updated 9 times
Summary
This study tests whether adding platelet-rich fibrin (PRF), made from a patient's own blood, to standard surgery improves healing of bone and gum damage around dental implants. Forty adults with peri-implantitis will be randomly assigned to receive either surgery with PRF or surgery alone. After 12 months, X-rays and clinical exams will compare bone fill and pocket depth between the two groups.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Periodontology, University of Bern
RECRUITINGBern, 3010, Switzerland
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
platelet-rich fibrin (PRF)
What this could lead to
If it works, this could point toward a better treatment for peri-implantitis, helping to save implants and reduce bone loss.
What could go wrong
This is a small, early-stage trial with only 40 participants, so results may not apply widely. PRF may not provide extra benefit over standard surgery.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.