Can your own blood help save a failing dental implant?

NCT ID NCT06679283

Recruiting now Disease control Sponsor: University of Bern Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding platelet-rich fibrin (PRF), made from a patient's own blood, to standard surgery improves healing of bone and gum damage around dental implants. Forty adults with peri-implantitis will be randomly assigned to receive either surgery with PRF or surgery alone. After 12 months, X-rays and clinical exams will compare bone fill and pocket depth between the two groups.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: platelet-rich fibrin (PRF)
What this could lead to: If it works, this could point toward a better treatment for peri-implantitis, helping to save implants and reduce bone loss.
What could go wrong: This is a small, early-stage trial with only 40 participants, so results may not apply widely. PRF may not provide extra benefit over standard surgery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bone resorption disease Peri-Implantitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BONE RESORPTION PERI IMPLANTITIS PLATELET RICH FIBRIN

Contacts and locations

Locations

Department of Periodontology, University of Bern
RECRUITING

Bern, 3010, Switzerland

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