Can smoking sabotage dental implants? a deep dive into immune signals

NCT ID NCT07750171

First seen Aug 06, 2026 · Last updated Aug 07, 2026 · Updated 1 time

Summary

This study investigates how smoking influences the immune response around dental implants, comparing smokers and non-smokers with healthy implants, gum inflammation (mucositis), or more severe implant-related bone loss (peri-implantitis). By analyzing fluid samples from around the implants, researchers aim to measure key inflammatory and immune markers. The goal is to understand how smoking alters the body's defense mechanisms and to identify potential biomarkers for assessing disease risk and severity.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this research could identify biological markers that help assess the risk and severity of peri-implant diseases, potentially guiding personalized prevention and treatment strategies.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The findings may not apply to all populations, and the identified markers may not be clinically useful without further validation.

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Conditions

The condition(s) this trial relates to.

Peri-Implantitis Smoking

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Gazi University

    RECRUITING

    Ankara, Ankara, 06510, Turkey (Türkiye)

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