Gum disease bone repair: collagen matrix takes on bone mineral in new trial

NCT ID NCT06676826

First seen Nov 01, 2025 · Last updated Jun 23, 2026 · Updated 32 times

Summary

This study tests two materials for filling bone defects caused by advanced gum disease: a collagen matrix and a bovine bone mineral. Eighty adults with deep gum pockets will receive one of the materials during surgery. Researchers will measure changes in gum attachment and bone healing over 12 months to see which material works better.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Bern

    RECRUITING

    Bern, 3010, Switzerland

    Contact Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

volume-stable collagen matrix (VCMX) or deproteinized bovine bone mineral with 10% collagen (DBBM)

What this could lead to

If successful, this could show that a collagen matrix is a good alternative to bone mineral for repairing gum-related bone damage, potentially simplifying treatment.

What could go wrong

This is a small, early-stage trial (80 people) comparing two materials, not testing a new drug. Results may not apply to all patients, and long-term benefits are uncertain.

Conditions

The condition(s) this trial relates to.

periodontal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.