Gum bone repair: collagen or bone mineral – which works better?

NCT ID NCT06676826

Recruiting now Disease control Sponsor: University of Bern Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two materials used to fill bone defects caused by gum disease: a collagen matrix and a bovine bone mineral. 80 adults with advanced periodontitis will receive one of the two during surgery. Researchers will measure changes in gum attachment and other healing signs over 12 months to see which material performs better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: volume-stable collagen matrix (VCMX) or deproteinized bovine bone mineral with 10% collagen (DBBM)
What this could lead to: If successful, this could show that a collagen matrix is a good alternative to bone mineral for repairing gum-related bone damage, potentially simplifying treatment.
What could go wrong: This is a small, early-stage trial (80 people) comparing two materials. Results may not apply to all patients, and long-term benefits are uncertain.

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Conditions

The condition(s) this trial relates to.

periodontal disorder periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIODONTAL DISEASES

Contacts and locations

Locations

University of Bern
RECRUITING

Bern, 3010, Switzerland

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