Could a gel make root canal surgery less painful?
NCT ID NCT07501585
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This study tests whether applying a special gel (cross-linked hyaluronic acid) during root-end surgery helps the gums heal faster and reduces pain afterward. About 46 adults with a tooth infection that didn't heal after standard root canal treatment will take part. Half will get the gel during surgery, and half will have surgery alone, with follow-up for one year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
cross-linked hyaluronic acid
What this could lead to
If it works, this could mean faster healing and less pain after root-end surgery for people with persistent tooth infections.
What could go wrong
This is a small early-stage trial with only 46 participants, so results may not apply to everyone. The benefit over standard surgery alone may be small or absent.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Praktika 1
RECRUITINGMoscow, 127006, Russia
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••