Root canal battle: which medicament kills more bacteria?

NCT ID NCT07671326

Recruiting now Disease control Sponsor: Medipol University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study tests two different medicines placed inside root canals to kill bacteria in teeth with chronic infection. 24 adults with infected molars will receive either a bioceramic or a calcium hydroxide paste. Researchers measure bacterial levels before and after treatment to see which works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Bio-C Temp (bioceramic) and UltraCal XS (calcium hydroxide)
What this could lead to: If one medicament proves more effective at killing bacteria, it could improve success rates for root canal treatments and reduce the need for retreatment.
What could go wrong: This is a small, early-stage study with only 24 participants, so results may not apply to all patients. The outcome is based on bacterial levels, not long-term tooth survival.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic apical periodontitis dental abscess periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INTRACANAL MEDICAMENTS PERIAPICAL PERIODONTITIS ROOT CANAL INFECTION

Contacts and locations

Locations

Istanbul Medipol University
RECRUITING

Istanbul, Istanbul, 34230, Turkey (Türkiye)

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