Root canal battle: which medicament kills more bacteria?

NCT ID NCT07671326

First seen Jun 27, 2026 · Last updated Jun 30, 2026 · Updated 2 times

Summary

This study tests two different medicines placed inside root canals to kill bacteria in teeth with chronic infection. 24 adults with infected molars will receive either a bioceramic or a calcium hydroxide paste. Researchers measure bacterial levels before and after treatment to see which works better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Bio-C Temp (bioceramic) and UltraCal XS (calcium hydroxide)

What this could lead to

If one medicament proves more effective at killing bacteria, it could improve success rates for root canal treatments and reduce the need for retreatment.

What could go wrong

This is a small, early-stage study with only 24 participants, so results may not apply to all patients. The outcome is based on bacterial levels, not long-term tooth survival.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

chronic apical periodontitis dental abscess periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Istanbul Medipol University

    RECRUITING

    Istanbul, Istanbul, 34230, Turkey (Türkiye)

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••