Chill out tooth pain: cooling inside of tooth during root canal may ease ache

NCT ID NCT07710833

Completed Symptom relief Sponsor: Recep Tayyip Erdogan University Source: ClinicalTrials.gov ↗

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study tests whether using cooled liquid to clean the inside of a tooth during root canal treatment can reduce pain afterward. It includes adults with certain tooth conditions who need a root canal. The approach involves comparing cooled versus room-temperature irrigation to see which leads to less discomfort.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: cooled sodium hypochlorite (NaOCl) irrigation during root canal treatment
What this could lead to: If effective, this simple cooling technique could become a standard way to reduce pain after root canal treatment.
What could go wrong: This is a small, early-stage trial, so results may not apply to all patients or tooth types. The cooling effect on pain may be minimal or no better than room-temperature irrigation.

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Conditions

The condition(s) this trial relates to.

periapical periodontitis pulpitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASYMPTOMATIC IRREVERSIBLE PULPITIS CRYOTHERAPY PERIAPICAL PERIODONTITIS

Contacts and locations

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Locations

Recep Tayyip Erdoğan University Faculty of Dentistry, Department of Endodontics

Rize, Centre, Turkey (Türkiye)

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