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Could the way a dentist moves a tiny file ease root canal pain?

NCT ID NCT07714733

Symptom relief Sponsor: Alanya Alaaddin Keykubat University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 20, 2026 · Last updated Jul 21, 2026 · Updated 1 time

Summary

This trial looks at whether changing how the dentist's tool moves during a root canal can reduce pain afterward. Adults with an infected lower premolar will get standard root canal treatment, but the file system will use either a continuous spin or a back-and-forth motion, with different stopping modes. Pain levels and painkiller use will be tracked for a week. The goal is to find a more comfortable way to do this common dental procedure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
root canal treatment with a single nickel-titanium file system using rotary or reciprocating motion and different apical modes
What this could lead to
If successful, this could help dentists choose settings that reduce pain after root canal treatment, making the procedure more comfortable.
What could go wrong
This is a small, early-stage trial focused on pain, not on curing the underlying infection. Results may not apply to all tooth types or patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jul 2026

An estimate. Start dates often move.

Expected to finish

Mar 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults aged 18-70 years * Systemically healthy individuals (ASA I) * Mandibular premolar teeth diagnosed with chronic apical periodontitis * Periapical Index (PAI) score ≥ 3 confirmed radiographically * Teeth indicated for single-visit root canal treatment * Patients able to understand and complete the Visual Analog Scale (VAS) * Written informed consent provided Exclusion Criteria: * Patients with systemic diseases or medically compromised conditions * Pregnant or breastfeeding women * Patients with uncontrolled diabetes mellitus * Use of analgesics or antibiotics within the previous 7 days * Teeth with root resorption * Teeth with immature apices * Previously endodontically treated teeth * Patients unable to provide informed consent

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Conditions

The condition(s) this trial relates to.

chronic apical periodontitis Pain, Postoperative periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Apical periodontitis Postoperative pain after endodontic treatment

How to take part

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  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

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