Can a laser beam ease pain after Root-End surgery?

NCT ID NCT06574152

First seen Aug 17, 2026 · Last updated Aug 17, 2026

Summary

This trial tests whether photobiomodulation (PBM), a type of low-level laser therapy, can reduce pain and improve healing after endodontic microsurgery—a procedure to treat infections at the tip of a tooth root. About 90 adults needing this surgery will receive either real PBM or a sham (inactive) treatment applied to the surgical incision. Researchers will measure pain levels and how well the incision heals in the days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Photobiomodulation (PBM) using a 660 nm diode laser applied to the surgical site after endodontic microsurgery
What this could lead to
If effective, this could offer a simple, drug-free way to reduce post-surgical pain and speed up healing after root-end surgery.
What could go wrong
This is a small, early-stage trial, and results may not apply to all patients. The effect on pain and healing may be modest or no better than a sham treatment.

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Conditions

The condition(s) this trial relates to.

dental pulp disorder Periapical Diseases periapical granuloma periapical periodontitis Radicular Cyst Tooth, Nonvital

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • The University of Texas Health Science Center at Houston

    RECRUITING

    Houston, Texas, 77030, United States

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