APICAL PERIODONTITIS
Clinical trials for APICAL PERIODONTITIS explained in plain language.
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Toothache relief: could a common painkiller beat standard root canal medicine?
Disease control Recruiting nowThis study compares two medications placed inside the tooth after a failed root canal: standard calcium hydroxide and the painkiller diclofenac sodium. Sixty patients with persistent infection around the tooth root will be randomly assigned to one of the two treatments. Healing w…
Matched conditions: APICAL PERIODONTITIS
Phase: NA • Sponsor: Mustafa Kemal University • Aim: Disease control
Last updated Jun 27, 2026 13:05 UTC
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Could vinegar and a laser beat tooth infections in diabetes?
Disease control Recruiting nowThis study tests whether a diode laser, apple cider vinegar, or the herb Gymnema Sylvestre can better disinfect root canals in people with type 2 diabetes who have a tooth infection called apical periodontitis. Ninety participants will be split into groups receiving different com…
Matched conditions: APICAL PERIODONTITIS
Phase: NA • Sponsor: Sharda University • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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Can a Blood-Derived gel save infected teeth after failed root canals?
Disease control Recruiting nowThis study compares standard root canal retreatment with a regenerative method using injectable platelet-rich fibrin (i-PRF) in 140 adults with persistent tooth infections. Participants are randomly assigned to one of the two treatments and followed for two years to assess healin…
Matched conditions: APICAL PERIODONTITIS
Phase: NA • Sponsor: Marmara University • Aim: Disease control
Last updated Jun 27, 2026 09:11 UTC
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Could a special MRI replace dental X-Rays for jaw and tooth issues?
Diagnosis Recruiting nowThis study aims to see if a special MRI designed for teeth can diagnose jaw joint disorders, tooth infections, and help plan dental implants as well as or better than traditional X-rays. About 470 adults needing dental imaging will get both an MRI and standard X-rays, and the res…
Matched conditions: APICAL PERIODONTITIS
Phase: NA • Sponsor: University of Aarhus • Aim: Diagnosis
Last updated Jun 27, 2026 12:29 UTC
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Can a better rinse ease root canal pain?
Symptom relief Recruiting nowThis study compares two different irrigation techniques used during root canal retreatment to see which one leads to less pain afterward. About 100 adults with a previous root canal and ongoing infection will take part. The goal is to find a simple way to improve comfort after th…
Matched conditions: APICAL PERIODONTITIS
Phase: PHASE4 • Sponsor: TC Erciyes University • Aim: Symptom relief
Last updated Jun 27, 2026 12:35 UTC
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New root canal technique could mean less pain for patients
Symptom relief Recruiting nowThis study tests a new way to do root canals that skips the manual step of scouting and widening the canal by hand. Instead, dentists use a special rotary file from the start. The goal is to see if this causes less pain after the procedure compared to the traditional method. The …
Matched conditions: APICAL PERIODONTITIS
Phase: NA • Sponsor: Alexandria University • Aim: Symptom relief
Last updated Jun 27, 2026 08:12 UTC
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Laser zaps pain after root canal failure
Symptom relief Recruiting nowThis study tests whether using a special laser to disinfect the root canal can lower inflammation and pain after a root canal has failed. Fifty-two adults with a failed root canal and a visible infection on X-ray will receive either standard cleaning plus the laser or standard cl…
Matched conditions: APICAL PERIODONTITIS
Phase: NA • Sponsor: Al-Azhar University • Aim: Symptom relief
Last updated Jun 26, 2026 14:09 UTC
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Why do french dentists pull baby teeth? a new survey aims to find out
Knowledge-focused Recruiting nowThis study surveys 100 French dentists who treat children to understand why they often choose extraction for non-vital baby teeth, even though effective alternatives like pulpectomy exist. The goal is to collect and analyze their treatment choices, reservations, and decision-maki…
Matched conditions: APICAL PERIODONTITIS
Sponsor: University Hospital, Strasbourg, France • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC