APICAL PERIODONTITIS
Clinical trials for APICAL PERIODONTITIS explained in plain language.
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New root canal sealer tested for less pain and faster healing
Symptom relief OngoingThis study looks at how two different root canal filling materials affect pain and healing in people with an infected tooth root. Sixty-four healthy adults with a single-rooted tooth that has not been treated before will receive a root canal using one of two sealers. Pain is trac…
Matched conditions: APICAL PERIODONTITIS
Phase: NA • Sponsor: Ankara Yildirim Beyazıt University • Aim: Symptom relief
Last updated May 17, 2026 03:41 UTC
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Laser tooth cleaning may beat standard sonic method for root canal healing
Symptom relief OngoingThis study compares two ways to clean infected root canals during a single dental visit: laser-activated irrigation versus sonic-activated irrigation. Sixty adults with chronic tooth infections needing revision will be randomly assigned to one method. Researchers will measure pai…
Matched conditions: APICAL PERIODONTITIS
Phase: NA • Sponsor: University of Zagreb • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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Could a common antioxidant improve root canal recovery?
Symptom relief OngoingThis study tests whether adding N-acetylcysteine (NAC) to standard root canal treatment can reduce pain and improve healing in people with infected, dead teeth. Forty adults with mature teeth and signs of infection around the root tip will receive either NAC or a standard medicat…
Matched conditions: APICAL PERIODONTITIS
Phase: PHASE2 • Sponsor: Alexandria University • Aim: Symptom relief
Last updated May 15, 2026 11:54 UTC
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Which root canal filling hurts less? new study aims to find out
Symptom relief OngoingThis study looks at two different medicines placed inside a tooth during root canal treatment to see which one causes less pain and helps the infection heal better. Eighty adults with infected front teeth will receive one of the two medicines and report their pain levels over a w…
Matched conditions: APICAL PERIODONTITIS
Phase: NA • Sponsor: Ege University • Aim: Symptom relief
Last updated May 12, 2026 13:43 UTC
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Ozone water tested as root canal rinse in new study
Knowledge-focused OngoingThis study looks at whether ozone water, used during root canal treatment, affects oxidative stress (a measure of cell damage) better than standard saline. Sixty adults with a painless tooth infection called apical periodontitis will be randomly assigned to receive either ozone o…
Matched conditions: APICAL PERIODONTITIS
Phase: NA • Sponsor: KEZBAN MELTEM ÇOLAK • Aim: Knowledge-focused
Last updated May 17, 2026 03:40 UTC