New dental sealer could improve root canal healing

NCT ID NCT03732170

Ongoing Disease control Sponsor: National University Hospital, Singapore Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two types of dental sealers used during root canal treatment: TotalFill (a bioceramic sealer) and AH Plus. The goal is to see which one leads to better healing of infections at the tooth root tip. 170 teeth from adults at a dental clinic in Singapore are being studied, with X-rays and pain scores used to track outcomes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: TotalFill® Bioceramic sealer and AH plus® sealer (dental sealers used during root canal treatment)
What this could lead to: If TotalFill works better, it could improve healing of tooth infections after root canals, reducing the need for retreatment.
What could go wrong: This is a single-center trial with 170 teeth, so results may not apply to everyone. The study is not yet complete, and the difference between sealers may be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ROOT CANAL OBTURATION

Contacts and locations

Locations

National University Hospital, Singapore

Singapore, 119085, Singapore

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Other studies related to the condition(s) this trial covers.