Root canal showdown: which paste eases pain best?

NCT ID NCT07210177

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests two different pastes placed inside the tooth between root canal visits to see which one reduces pain and helps the bone heal better. Eighty adults with infected but painless front teeth will receive either Bio-C Temp or Metapaste. Pain is tracked for a week, and X-rays check healing over two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Bio-C Temp (calcium silicate-based) and Metapaste (calcium hydroxide-based) intracanal medicaments

What this could lead to

If one medicament works better, it could reduce pain and speed healing after root canal treatment.

What could go wrong

This is a small, early-stage study (80 people) comparing two existing materials, so any difference may be small or not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ege University

    Izmir, Bornova, 35030, Turkey (Türkiye)