Can cold therapy and special rinses tame tooth pain after pulpotomy?

NCT ID NCT07764666

ENROLLING_BY_INVITATION Symptom relief Sponsor: Abdelrahman Refaat Khalaf Ahmed Source: ClinicalTrials.gov ↗

First seen Aug 14, 2026 · Last updated Aug 14, 2026

Summary

This trial asks whether using sodium hypochlorite or saline to rinse the tooth, with or without cold therapy (cryotherapy), can reduce pain after a pulpotomy in permanent molars. Adults aged 15-40 with symptomatic irreversible pulpitis will undergo the procedure, and their pain will be tracked for a week. The study also checks overall success, such as absence of pain and tooth vitality.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Sodium hypochlorite irrigation and cryotherapy (cold application) during pulpotomy
What this could lead to: If effective, this could point to a simple way to reduce post-operative pain and improve success after vital pulp therapy, making dental procedures more comfortable.
What could go wrong: This is a very small early trial (3 participants), so results may not apply broadly. Pain is subjective, and the benefits of cryotherapy or different irrigants may not be significant.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

POST-OPERATIVE PAIN VITAL PULP THERAPY

Contacts and locations

Locations

Faculty of Oral and Dental Medicine future university, Cairo,

Cairo, Cairo Governorate, 11835, Egypt

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