Cure My Disease

Don't miss your cure!

 Log in / Sign up

Chest nerve block may slash opioid use after heart surgery

NCT ID NCT06546722

Symptom relief Sponsor: Saint-Joseph University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This trial tests whether a targeted nerve block called the Transversus Thoracic Plane Block (TTPB) can reduce pain after cardiac surgery more effectively than standard painkillers. It involves 150 adults scheduled for heart surgery through a chest incision. Researchers also compare giving the block before surgery versus at the end, to see which timing works best.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
a nerve block injection of local anesthetic between chest muscles
What this could lead to
If effective, TTPB could become a standard way to manage pain after heart surgery, reducing opioid use and speeding recovery.
What could go wrong
This is a single-center study with 150 participants, so results may not apply broadly. The block carries rare risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

150 people

The number who actually took part.

Started

Sep 2024

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: \- All patients scheduled for cardiac surgery via sternotomy under cardiopulmonary bypass Exclusion Criteria: * Previous cardiac surgery * Urgent surgery * Pregnant women * Allergy to local anesthetics * Opioid dependence * Low ejection fraction \< 30% * Presence or onset of cognitive or neurological disorders preventing pain assessment * Infection at injection sites * Coagulopathy * Patients on dual antiplatelet therapy * Renal insufficiency with Glomerular filtration rate (GFR) \< 30 mL/min * History of thoracic radiotherapy * History of mastectomy

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Cardiac surgery are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiac surgery Post operative pain Transversus thoracic plane block

Contacts and locations

Locations

  • Hotel Dieu de France

    Beirut, 166830, Lebanon

More trials for these conditions

Other studies related to the condition(s) this trial covers.