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Chest nerve block may slash opioid use after heart surgery

NCT ID NCT06546722

Completed Symptom relief Sponsor: Saint-Joseph University Source: ClinicalTrials.gov ↗

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This trial tests whether a targeted nerve block called the Transversus Thoracic Plane Block (TTPB) can reduce pain after cardiac surgery more effectively than standard painkillers. It involves 150 adults scheduled for heart surgery through a chest incision. Researchers also compare giving the block before surgery versus at the end, to see which timing works best.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a nerve block injection of local anesthetic between chest muscles
What this could lead to
If effective, TTPB could become a standard way to manage pain after heart surgery, reducing opioid use and speeding recovery.
What could go wrong
This is a single-center study with 150 participants, so results may not apply broadly. The block carries rare risks like bleeding or infection.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC SURGERY POST OPERATIVE PAIN TRANSVERSUS THORACIC PLANE BLOCK

Contacts and locations

Locations

  • Hotel Dieu de France

    Beirut, 166830, Lebanon

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