Laser zaps pain after root canal failure

NCT ID NCT07141459

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tests whether using a special laser to disinfect the root canal can lower inflammation and pain after a root canal has failed. Fifty-two adults with a failed root canal and a visible infection on X-ray will receive either standard cleaning plus the laser or standard cleaning alone. The main goal is to measure levels of inflammatory chemicals and pain scores after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

810 nm diode laser disinfection

What this could lead to

If it works, this could offer a better way to manage pain and infection after a failed root canal, reducing the need for repeat procedures.

What could go wrong

This is a small, early-stage trial with only 52 participants, so results may not apply to everyone. The laser is an add-on to standard care, not a replacement.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

periapical periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • from the outpatient clinic of Endodontic Department, Faculty of Dental Medicine for Girls, Al-Azhar University

    RECRUITING

    Cairo, Egypt

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••