Al-azhar University

This study looks at whether taking coenzyme Q10 and vitamin C, alone or together, can improve healing and reduce dark gum color after surgical gum depigmentation. The trial involves 20 healthy adults with dark gums who undergo a simple scalpel procedure to remove pigmented tissue…

This trial investigates whether adding low-intensity pulsed ultrasound to standard twin-block braces can improve jaw joint growth in teenagers with a receding lower jaw (skeletal class II malocclusion). The study involves 24 participants who will receive the combined treatment. T…

This study tests whether taking omega-3 fatty acids (fish oil) plus low-dose aspirin can improve gum disease treatment in smokers with advanced periodontitis. Participants receive these supplements or a placebo alongside standard deep-cleaning procedures. The trial measures chang…

This study tests whether coating a dental implant with erythropoietin gel helps it bond more firmly with the jawbone. Twenty-four adults needing a front tooth implant will be randomly assigned to get either a gel-coated or standard implant. The main goal is to measure implant sta…

This study tests whether two nano-sized pastes—nano-calcium hydroxide and nano-chitosan—can reduce inflammation and pain in people who need a second root canal treatment. The trial will enroll 63 adults with a single-rooted tooth that has a persistent infection and no current pai…

This study compares two types of tiny screws used in braces to help move upper front teeth. One type has a special silver-hydroxyapatite coating, while the other is uncoated. Researchers want to see if the coated screws are more successful and allow faster tooth movement. The tri…

This study compares two pastes used to sterilize infections and repair tissue in baby molars that have died. One paste contains zinc oxide mixed with 6-gingerol (a compound from ginger), and the other is a standard triple antibiotic paste. Sixty children aged 4 to 8 with at least…

This study looks at whether adding echinacea (Immulant®) to standard care can reduce symptoms and parasite levels in children aged 5–12 with weakened immune systems who have cryptosporidiosis, a diarrheal infection. About 60 children will take part. The goal is to see if the supp…

This study tests two mouthwashes—one with probiotics (good bacteria) and one with ethyl lauroyl arginate—to see which better reduces cavity-causing bacteria, plaque, and acidity in the mouths of Egyptian children aged 6 to 12. Researchers will measure bacteria levels and plaque b…

This study tests a new effervescent (fizzing) powder containing 5-fluorouracil to treat vitiligo, a condition that causes white patches on the skin. Sixty people with stable vitiligo will apply either the new fizzing powder or plain 5-fluorouracil powder to their patches. The goa…

This study tests whether using an 810 nm diode laser during root canal retreatment helps the bone around the tooth heal better. Forty adults with a failed root canal and a visible infection will receive standard retreatment plus either laser disinfection or a calcium hydroxide pa…

This study tests whether giving ozone gas through the rectum can help protect the brain in children who have suffered a brain injury. 120 children aged 1 month to 18 years will either receive up to 80 rectal ozone sessions plus standard rehab, or rehab alone. The main goal is to …

This study tests if making small holes in the jawbone (micro-osteoperforations) helps move front teeth more safely and effectively in people with a deep bite. 18 participants aged 15-25 will receive standard braces with or without the extra procedure. The goal is to see if it red…

This study tests whether vitamin C can lighten dark gums caused by excess melanin. Thirty adults with dark gums will receive vitamin C as a gel, through tiny needles (microneedling), or as injections (mesotherapy). Researchers will measure color changes and look at gum tissue und…

This study tests whether using a special laser along with standard ultrasonic cleaning can reduce pain and kill more bacteria after a root canal. About 120 adults with infected single-root teeth will be treated and asked to rate their pain. The goal is to find a better way to man…

This study tests whether giving vitamin D3 locally and using a minor surgical technique called corticision can make orthodontic tooth movement faster. Sixteen patients aged 13-20 who need premolar extractions will be followed for 12 weeks. The goal is to see if these methods safe…

This study looks at whether giving melatonin under the tongue before cataract surgery can reduce anxiety and help older adults relax. Sixty people aged 60 and older will receive either melatonin or a placebo. The goal is to find a safer alternative to standard sedatives that may …

This study tests whether adding dexmedetomidine or tramadol to standard paracetamol can reduce bladder discomfort caused by urinary catheters after kidney stone surgery. Sixty adults aged 20-50 will receive one of two drug combinations, and their pain and discomfort will be track…

This study tests three different ways to prevent pain from a tourniquet (a tight band that stops blood flow) during forearm surgery. Sixty adults having forearm surgery will be randomly assigned to receive one of three pain-blocking methods. The goal is to find which method works…

This study tests two methods of delivering a TAP block—a type of pain shot—after a planned C-section. One method uses ultrasound to guide the needle, the other is done by the surgeon during the operation. The goal is to see which approach provides better pain control and is faste…

This study tests whether a dose of melatonin, a natural sleep hormone, can reduce anxiety in children before surgery. 120 kids aged 4 to 14 will receive either a low dose, a higher dose, or a placebo 90 minutes before anesthesia. The goal is to see if melatonin works as well as o…

This study tests two different dental file systems—EdgeOne Fire (reciprocating motion) and Jizai (rotary motion)—to see which causes less pain during and after root canal treatment in upper premolars with infected pulp. Fifty-six adults with moderate spontaneous pain will be rand…

This study tests whether using a special laser to disinfect the root canal can lower inflammation and pain after a root canal has failed. Fifty-two adults with a failed root canal and a visible infection on X-ray will receive either standard cleaning plus the laser or standard cl…

This study looks at how two types of dental crowns—stainless steel and bioflex—affect oral hygiene and bacteria levels in children aged 4 to 8. Each child will get one crown of each type on opposite sides of the mouth. Researchers will measure plaque bacteria and gum health to se…

This study looks at 20 adults with hearing loss in one ear but a normal-looking eardrum. Doctors want to see how often their best guess about the cause matches what they find during a small ear surgery. The goal is to improve diagnosis and treatment for this tricky condition.

This study looks at how changing the air pressure in a patient's lungs during a tummy tuck (abdominoplasty) affects their breathing after surgery. Researchers will measure lung pressure before and after the surgeon tightens the belly muscles, and then check lung function afterwar…

This study observes 100 adults aged 20–40 who are having nose surgery (septorhinoplasty) to see if the length of time nasal packing is left in place affects the development of sore throat or pharyngitis. Participants will have their sore throat, swallowing difficulty, and throat …

This study looks at how well therapeutic plasma exchange (a blood-filtering procedure) works for people with autoimmune neurological diseases. Researchers at Al-Azhar University Hospitals will follow 60 Egyptian patients to see if their symptoms and daily function improve. The go…