Al-azhar University

This trial tests whether combining fractional carbon dioxide laser treatment with a topical metformin cream works better than laser alone for acanthosis nigricans—dark, velvety patches on the neck. About 34 adults with this condition will have one side of their neck treated with …

This trial tests a modified jaw surgery technique, called low sagittal medial ramus osteotomy, for people with severe bite misalignment (skeletal Class II or III malocclusion). The procedure aims to reposition the jaw with fewer complications than the standard surgery, particular…

This study tests two surgical techniques to treat stable white patches on the skin that are not caused by vitiligo. Both methods involve transplanting the patient's own skin cells, followed by laser therapy to boost color return. Twenty-two adults will each receive both treatment…

This study compares two fixed dental appliances—Quad Helix and Rapid Maxillary Expanders—for treating posterior crossbite in 20 Egyptian children aged 9-12. The goal is to see which device widens the upper jaw more effectively and causes less discomfort. Results could help dentis…

This study will test four different dental filling materials in 92 children aged 4-8 who have cavities in their baby molars. The fillings include newer materials like Cention N and Stela, as well as standard options like Beautifil II and resin-modified glass ionomer. Researchers …

This study will test whether a standardized set of emergency steps—including early screening, blood tests, fluids, and antibiotics—can improve survival for sepsis patients. Researchers will compare outcomes for 120 adults treated before and after the new protocol is introduced. T…

This study tests whether graphene oxide can successfully treat decayed baby teeth that need pulp therapy. 126 children will be split into groups receiving graphene oxide, standard materials like MTA or zinc oxide, or a lesion sterilization technique. The goal is to see which appr…

This study tests a new surgery for people whose shoulders keep dislocating. The surgeon uses a piece of the patient's own tendon to build up the shallow part of the shoulder socket. The goal is to make the joint more stable and prevent future dislocations. The study will include …

This study tests whether natural substances like grape seed extract and glycyrrhizin can replace antibiotics in a procedure to revive dead permanent teeth in children aged 7-13. The goal is to restore blood flow and promote root growth while reducing pain and infection. The trial…

This study will test three different materials—hyaluronic acid, TheraCal, and MTA—used to treat deep cavities in children's baby molars. Sixty-six kids aged 4 to 8 will receive one of the treatments, and researchers will check for pain, swelling, and X-ray changes over 12 months.…

This study checks if an artificial intelligence (AI) system can analyze dental X-rays as accurately as the standard manual method. About 55 people with crooked teeth or jaw issues will have their X-rays read by both AI and a human expert. The goal is to see if AI can be a reliabl…

This trial tests whether adding Acceptance and Commitment Therapy (ACT) to standard physiotherapy helps adults with chronic low back pain more than physiotherapy alone. About 64 adults aged 18-55 with non-specific low back pain lasting over 3 months will be randomly assigned to e…

This study tests whether low-intensity shock wave therapy, a non-surgical treatment applied over the lower abdomen, can ease overactive bladder symptoms in women who haven't found relief from standard treatments. Forty women will be randomly assigned to receive either the real th…

This study compares two types of ultrasound-guided nerve blocks to control pain after open inguinal hernia repair. 66 adults will receive either a lateral quadratus lumborum block or a combined ilio-inguinal/ilio-hypogastric/genitofemoral block. The goal is to see which method re…

This study tests three different doses of a drug called dexmedetomidine, given with spinal anesthesia, to see if it can prevent shivering after surgery. 120 adults having kidney stone removal will be randomly assigned to receive one of the three doses or a placebo. The goal is to…

This study tests whether injecting a small amount of local anesthetic through the epidural needle before inserting the catheter makes placement easier and more successful. Researchers will compare this method to the standard approach in 216 women requesting painless labor. The go…

This study tests whether adding dexamethasone (a steroid), dexmedetomidine (a sedative), or both to standard numbing medicine can prevent the intense pain that often occurs when a nerve block wears off after arm surgery. About 75 adults having elective upper limb surgery will be …

This study compares two ways of giving spinal anesthesia for planned C-sections: the standard single injection versus a sequential (two-part) injection. The goal is to see if the sequential method reduces the chance of a sudden drop in blood pressure, a common and risky side effe…

This study will test whether adding pain neuroscience education (learning how pain works) to standard back exercises helps people with chronic low back pain more than exercises alone. Forty adults aged 25 to 50 with pain lasting over 12 weeks will be randomly assigned to either e…

This study will test whether combining Pilates with resistance training can reduce pain, disability, and sleep problems in people with chronic low back pain. 110 participants will be split into three groups: one doing both Pilates and resistance training, one doing Pilates alone,…

This study tests whether adding a daily physical activity program to a structured exercise routine can reduce disability and improve mental health in people aged 60 and older with chronic low back pain. One hundred participants will be split into three groups: exercise plus activ…

This study looks at whether teaching people with chronic neck pain better sleep habits, along with standard physiotherapy exercises, can improve their sleep quality and reduce disability. 120 adults aged 20-55 with poor sleep and neck pain lasting over 3 months will be split into…

This study explores whether measuring how a woman's pupils react to light before spinal anesthesia can predict dangerous drops in blood pressure during planned cesarean sections. Researchers will observe 200 healthy pregnant women and track their pupil responses and blood pressur…

This study looks at how a small surgical procedure called corticision affects the body's response when pushing lower front teeth inward during orthodontic treatment. Researchers will measure certain chemicals in the gum fluid and track how much the teeth move. The study involves …

This study looks at whether a quick, painless eye ultrasound can predict which women will get a headache after spinal anesthesia for C-section. Researchers will measure the optic nerve sheath diameter before and after the spinal block in 150 women. The goal is to find a cutoff va…

This study tests whether applying a Vitamin D gel (calcitriol) to one side of the upper jaw can speed up the movement of a canine tooth during orthodontic treatment. Twenty-two people aged 13 to 35 who need premolar extractions will participate. The gel is applied only on one sid…