Al-azhar University
Clinical trials sponsored by Al-azhar University, explained in plain language.
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Liquorice gel takes on laser in gum disease showdown
Disease control CompletedThis study compared a liquorice nanogel to a diode laser as extra treatments for advanced gum disease (stage III). 27 adults with deep gum pockets received one of the two treatments alongside standard care. The goal was to see which approach better reduced harmful bacteria and im…
Phase: PHASE3 • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 12:36 UTC
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New study compares two surgical techniques for a common birth defect in boys
Disease control CompletedThis study looked at 80 children with a type of hypospadias (a birth defect where the urine opening is not at the tip of the penis) who had a narrow urethral plate. The researchers compared two different surgical repair methods to see which had fewer complications and better cosm…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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Could a tree extract beat bad breath in kids with braces?
Disease control CompletedThis study tested whether a mouthwash made from Moringa extract can reduce bacteria in the mouths of children aged 8 to 12 who wear removable braces. Sixty children were split into two groups: one used the Moringa mouthwash daily, the other followed standard oral hygiene. Researc…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Dental device showdown: which expander moves molars best?
Disease control CompletedThis study tested two different dental expanders in 30 teenagers aged 15-18 who needed their upper molars moved backward to correct a Class II bite. One device was a self-activated Leaf Expander and the other a conventional Hyrax Expander, both anchored to the jawbone. The goal w…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Denture showdown: which attachment keeps your jawbone healthier?
Disease control CompletedThis completed study tested two types of attachments (ball-and-socket vs Equator) for lower jaw implant-supported dentures in 24 adults aged 55-60. Researchers measured bone loss around the implants and how bite forces were distributed. The goal was to see which attachment provid…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 12:03 UTC
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Diabetes drug may boost dental implant success, small study finds
Disease control CompletedThis study looked at whether adding 1% metformin gel to a bone graft improves bone healing and implant stability in people getting immediate dental implants. Twenty adults aged 18 to 40 with a non-restorable tooth in the front or premolar area took part. The researchers measured …
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Hip replacement showdown: which surgery gets seniors back on their feet faster?
Disease control CompletedThis study compared two types of hip replacement surgery in active elderly patients who broke their hip. One group received a total hip replacement (replacing the ball and socket), while the other had a partial replacement (replacing only the ball). The goal was to see which surg…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 09:06 UTC
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Knee surgery showdown: which repair technique wins for meniscus root tears?
Disease control CompletedThis study compared two arthroscopic surgical techniques for repairing a tear at the back of the knee's medial meniscus (a common injury that can lead to arthritis). Forty adults aged 20-50 with this tear were randomly assigned to receive either a transtibial pullout suture repai…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New combo therapy may save bladders in bladder cancer patients
Disease control CompletedThis completed study tested a three-step treatment for muscle invasive bladder cancer: chemotherapy, then a minimally invasive surgery to remove the tumor, followed by radiation. The goal was to treat the cancer while keeping the bladder intact, which could improve quality of lif…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 09:04 UTC
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New jaw expander could improve smiles for kids with cleft lip and palate
Disease control CompletedThis study tested a new device called the Leaf Self Expander to widen the upper jaw in 20 children with cleft lip and palate. The device was compared to the standard rapid maxillary expander. Researchers used 3D scans to measure changes in bone and tooth position. The goal was to…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 09:01 UTC
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Flexible dentures may beat rigid ones for implant fit
Disease control CompletedThis study tested two types of denture material for people with no teeth who got implant-supported overdentures. Sixteen patients received either a standard acrylic denture or a flexible resin one. Researchers measured gum pocket depth, plaque buildup, and Candida yeast growth to…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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New surgery offers hope for kids with stubborn constipation
Disease control CompletedThis study tested a two-part surgery for children with severe constipation that didn't get better with standard treatments. The surgery removes part of the colon and creates a small opening in the belly for enemas. The goal was to reduce accidental stool leakage (soiling). The st…
Phase: PHASE4 • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Which surgery works best for kids with hirschsprung disease? new study compares two techniques
Disease control CompletedThis study compared two types of laparoscopic surgery (Swenson-like and Soave) for children with Hirschsprung disease, a condition where nerve cells are missing in part of the colon. Forty children were treated at Al-Azhar University Hospitals, and researchers measured bowel func…
Phase: PHASE4 • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 07:52 UTC
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Less invasive parotid tumor surgery may reduce nerve damage risk
Disease control CompletedThis completed trial compared two surgical techniques for removing benign parotid gland tumors: the standard superficial parotidectomy and a newer, less invasive intracapsular parotidectomy. The study involved 120 adults aged 20-65 with confirmed benign tumors. The goal was to se…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Could adding cabergoline boost ovulation in PCOS?
Disease control CompletedThis study tested whether adding cabergoline to the standard drug letrozole helps women with PCOS ovulate more often. One hundred women took either letrozole alone or letrozole plus cabergoline. Researchers tracked ovulation using ultrasound starting on day 10 of the menstrual cy…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 26, 2026 16:32 UTC
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Tiny bone holes may help adults avoid jaw surgery
Disease control CompletedThis completed study tested a special dental expander combined with tiny bone perforations (MOPs) to widen the upper jaw in 14 adults aged 17-23 with a narrow jaw and crossbite. The goal was to see if this less invasive method could effectively expand the jaw without major surger…
Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 26, 2026 14:30 UTC
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Flavonoid gel boosts bone density around dental implants in small trial
Disease control CompletedThis study tested a gel made from kaempferol, a natural flavonoid, to see if it helps bone heal better around dental implants. Thirty patients with a missing back tooth received the gel during implant surgery. Those who got the gel showed higher levels of a bone-healing marker an…
Phase: NA • Sponsor: Al-Azhar University • Aim: Disease control
Last updated Jun 26, 2026 13:37 UTC
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Nose surgery may quiet snoring and ease sleep apnea
Symptom relief CompletedThis study looked at whether surgery to fix a blocked nose can improve snoring and sleep apnea in adults. Thirty people with nasal obstruction and sleep apnea had surgery. The main goal was to see if their breathing pauses during sleep (measured by the apnea-hypopnea index) got b…
Phase: NA • Sponsor: Al-Azhar University • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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Could skipping sedation help ventilated COPD patients recover faster?
Symptom relief CompletedThis study looked at 100 adults with COPD who needed a breathing tube and a ventilator. It compared two approaches: giving sedation with daily breaks versus giving no sedation at all. The goal was to see which method leads to more days off the ventilator and fewer complications i…
Phase: PHASE2 • Sponsor: Al-Azhar University • Aim: Symptom relief
Last updated Jun 27, 2026 13:01 UTC
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New breathing device may offer alternative for COPD emergencies
Symptom relief CompletedThis study tested a new breathing support method (HVNI) against standard non-invasive ventilation (NIV) in 66 COPD patients with dangerously high carbon dioxide levels. The goal was to see if HVNI could safely lower carbon dioxide and reduce the need for a breathing tube. Results…
Phase: NA • Sponsor: Al-Azhar University • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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New study finds best denture attachment for seniors
Symptom relief CompletedThis study tested two different attachment systems (Equator and Novaloc) for lower dentures held in place by dental implants. The goal was to see which one helps dentures stay in place better and improves quality of life for people with no teeth. 26 adults aged 60-70 took part. T…
Phase: NA • Sponsor: Al-Azhar University • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Could selenium soothe painful mouth sores?
Symptom relief CompletedThis study tested whether a selenium gel can help treat oral lichen planus, a chronic condition that causes painful sores in the mouth. Fifty adults with the condition used either selenium gel, a standard steroid cream, or an immunosuppressant cream. The goal was to see if seleni…
Phase: PHASE4 • Sponsor: Al-Azhar University • Aim: Symptom relief
Last updated Jun 27, 2026 08:07 UTC
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New ultrasound technique spots hidden heart trouble in kids on dialysis
Knowledge-focused CompletedThis study tests whether advanced ultrasound techniques (2D and 3D speckle-tracking echocardiography) can detect early signs of heart muscle dysfunction in children aged 4 to 18 with end-stage kidney disease who have been on dialysis for at least a year. Researchers aim to see if…
Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jul 02, 2026 02:00 UTC
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Bite battle: clear aligners vs. braces in crowding fix
Knowledge-focused CompletedThis completed study looked at how clear aligners and fixed braces affect bite forces after treating mild front-tooth crowding. Twelve people aged 14-22 with mild crowding and no extractions were treated with either clear aligners or fixed braces. The goal was to see which method…
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Computer navigation in sinus surgery: a closer look at outcomes
Knowledge-focused CompletedThis study looked at whether using computer-assisted navigation during sinus surgery helps people with nasal polyps. Researchers compared surgery with and without this technology in 40 patients. They tracked how often polyps came back and how many complications occurred.
Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:30 UTC
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Hot climate may raise bleeding risk after heart surgery, study suggests
Knowledge-focused CompletedThis study looked at 400 Egyptian patients who had open-heart surgery to see if living in a hot climate affects bleeding afterward. Researchers compared patients from hot regions (Upper Egypt) with those from milder regions (Lower Egypt). The goal was to understand if climate pla…
Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Timing matters: study reveals optimal gap between C-Sections
Knowledge-focused CompletedThis study looked at 201 women who had repeat C-sections to find the best time gap between surgeries. Researchers compared intervals from less than 12 months to over 48 months, tracking complications like bleeding, injuries, and blood transfusions. The goal is to help doctors and…
Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Diabetes may worsen eye cell loss after cataract surgery, study finds
Knowledge-focused CompletedThis study looked at 100 people aged 40 and older who had cataract surgery. Half had type 2 diabetes and half did not. Researchers measured changes in the thin cell layer on the inside of the cornea before and after surgery to see if diabetes affects recovery. The goal is to help…
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC
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Smoking may slow gum healing after deep cleaning, study finds
Knowledge-focused CompletedThis study looked at how smoking affects gum healing after non-surgical treatment for stage II gum disease. Researchers measured two proteins (PLAP-1 and Sclerostin) in the gum fluid of 36 patients—both smokers and non-smokers—before and after deep cleaning. The goal was to see i…
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:11 UTC
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Diabetes may impact dental pulp treatment success
Knowledge-focused CompletedThis study examined whether type 2 diabetes influences how well a dental procedure called pulpotomy works in adults. Researchers compared 70 diabetic and non-diabetic patients who had a molar treated for irreversible pulpitis. They checked the tooth's health, symptoms, and X-ray …
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC
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Ultrasound reveals best breathing tactics to stop lungs from collapsing after surgery
Knowledge-focused CompletedThis completed study tested two methods to prevent lung collapse after upper abdominal surgery: using a breathing machine with extra pressure (PEEP) alone, or adding a short breath-hold maneuver (RM). Both groups also received fluids. Researchers used lung ultrasound to check for…
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Dental bone graft showdown: which material works best for implants?
Knowledge-focused CompletedThis study tested two ways to rebuild jawbone for dental implants in 40 adults with narrow upper front jaws. One method used a block of bone from the chin mixed with cow-derived bone particles; the other used a synthetic material. Researchers measured bone width changes and compl…
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Tiny study pits drill against hammer for better dental implants
Knowledge-focused CompletedThis completed study tested two devices—a special drill (Densah Bur) and a magnetic hammer (Magnetic Mallet)—to see which better prepares a narrow jawbone for dental implants. Only 5 people took part, all with partial tooth loss and enough bone height but not enough width. The ma…
Phase: NA • Sponsor: Al-Azhar University • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:36 UTC