Can a tiny pinhole rebuild bone lost to gum disease?
NCT ID NCT07763223
First seen Aug 13, 2026 · Last updated Aug 14, 2026 · Updated 1 time
Summary
This trial tests a new, less invasive surgical approach for treating advanced periodontitis (stage III). Instead of lifting the gum, doctors access the damaged bone through a small pinhole, clean the area, and place a bone graft to encourage regeneration. The study includes adults aged 39-61 with deep gum pockets and specific bone defects. Over six months, the researchers will measure improvements in pocket depth, gum attachment, and bone fill to see if this technique is effective.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- A minimally invasive surgical procedure (Sub-junctional Pinhole Technique) using a xenogenic bone graft (Geistlich Bio-Oss) placed through a small pinhole without lifting the gum.
- What this could lead to
- If successful, this approach could offer a less invasive way to regenerate bone and gum support in advanced periodontitis, potentially saving teeth that might otherwise be lost.
- What could go wrong
- This is a very small early-stage trial (10 people), so results may not apply broadly. The procedure is surgical and carries risks like infection, pain, or graft failure, and long-term benefits are unproven.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Department of Periodontology, Faculty of Dentistry, Al-Azhar University, Cairo, Egypt
Cairo, Nasr City, 11675, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.