Your own blood may help heal gums and save teeth

NCT ID NCT07395726

Completed Disease control Sponsor: Armed Forces Institute of Dentistry, Pakistan Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether platelet-rich fibrin (PRF), made from a patient's own blood, can improve gum and bone regeneration after standard periodontal surgery. Sixty adults with chronic gum disease and bone defects were randomly assigned to surgery alone or surgery plus PRF. Researchers measured pocket depth, attachment levels, and bone fill over six months to see if PRF offers extra healing benefits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Platelet-Rich Fibrin (PRF)
What this could lead to: If it works, this could offer a simple, natural way to improve gum and bone healing after periodontal surgery, potentially reducing tooth loss.
What could go wrong: This is a small, completed trial with 60 participants. PRF may not provide significant extra benefit over standard surgery, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

chronic periodontitis periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PERIODONTAL INTRABONY DEFECTS PERIODONTITIS

Contacts and locations

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Locations

Armed Forces Institute of Dentistry

Rawalpindi, 46000, Pakistan

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