Smoking may slow gum healing after deep cleaning, study finds
NCT ID NCT07339670
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looked at how smoking affects gum healing after non-surgical treatment for stage II gum disease. Researchers measured two proteins (PLAP-1 and Sclerostin) in the gum fluid of 36 patients—both smokers and non-smokers—before and after deep cleaning. The goal was to see if smoking changes the body's healing response at a molecular level.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Non-surgical periodontal treatment (scaling, root planing, and Listerine mouthwash)
What this could lead to
If successful, this study could reveal how smoking interferes with gum healing, potentially leading to better treatment approaches for smokers with gum disease.
What could go wrong
This is a small, completed observational study with only 36 participants. It measures protein levels rather than long-term health outcomes, so results may not directly change treatment.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Faculty of Dental Medicine for Girls, Al-Azhar University
Cairo, Nasr City, 4450113, Egypt