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Could a common disinfectant improve dental cleanings for gum disease?

NCT ID NCT07712627

Disease control Sponsor: Ataturk University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This study tests whether using hypochlorous acid—a mild disinfectant—during deep dental cleaning helps treat early-stage periodontitis (gum disease) better than cleaning with water alone. Researchers will measure gum healing, pocket depth, and inflammation markers in 44 adults with Stage I or II periodontitis. The goal is to see if this simple addition can improve outcomes of standard non-surgical treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hypochlorous acid solution applied during dental cleaning
What this could lead to
If it works, this could offer a simple, antimicrobial boost to standard dental cleanings for early gum disease.
What could go wrong
This is a small, early-stage study with 44 participants, so results may not apply broadly. The added benefit over standard cleaning alone may be small.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

44 people

The number who actually took part.

Started

Oct 2025

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Individuals aged 18 to 65 years. 2. Systemically healthy individuals. 3. Diagnosis of Stage I or Stage II periodontitis according to the 2017 Classification of Periodontal Diseases. 4. Probing pocket depth (PPD) ≤5 mm and clinical attachment loss (CAL) ≤4 mm. 5. Presence of a sufficient number of teeth for periodontal evaluation. 6. Willingness to participate and ability to provide written informed consent. Exclusion Criteria: 1. Patients with contraindications to the use of ultrasonic instrumentation. 2. Pregnant or lactating women. 3. Patients receiving anti-inflammatory or antibiotic therapy. 4. Patients with systemic diseases or medical conditions. 5. Patients receiving continuous medication for any medical condition. 6. Patients who have undergone periodontal treatment within the previous 6 months. 7. Patients presenting with acute dental pain (e.g., pulpitis or apical/periodontal abscess). 8. Individuals who smoke or consume alcohol. 9. Presence of fewer than 15 teeth.

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Conditions

The condition(s) this trial relates to.

alveolar periostitis periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Periodontitis Periodontitis stage I Periodontitis stage II

Contacts and locations

Locations

  • Faculty of Dentistry, Atatürk University

    Erzurum, Erzurum, Turkey (Türkiye)

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