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Can a seaweed extract help bones regrow in the jaw?

NCT ID NCT07793851

Disease control Sponsor: Krishnadevaraya College of Dental Sciences & Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time

Summary

This trial tests whether a gel made from fucoidan, a compound found in seaweed, can improve healing and bone regrowth in people with gum disease. The study enrolls 5 systemically healthy adults aged 25 to 55 who have periodontitis with bone defects around teeth or implants. After placing the gel in the defects, researchers measure wound healing and changes in bone level using dental X-rays.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
fucoidan gel
What this could lead to
If it works, fucoidan gel could become a simple, natural aid to help gums heal and bone regrow after periodontal treatment.
What could go wrong
This is a very small case series with only 5 participants, so results may not apply broadly. The gel's effect on bone regeneration is uncertain and needs larger studies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

5 people

The number who actually took part.

Started

Jun 2025

Finished

Jun 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

All the patients who meet the eligible criteria will undergo Scaling and root planning (SRP) as a part of Phase I therapy. Patients with ≥6mm probing sites will undergo surgical therapy, patients presenting with different osseous defects will be treated with Fucoidan gel. A total of 5 samples will be allotted to different defects

Ages

25 to 55 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Systemically healthy patients between 25 to 55 years. * Stage II/III and Grade B periodontitis patient. * Osseous defects (intra bony defects, compromised bone support and around dental implants) Exclusion Criteria: * Patients with systemic diseases. * Smokers. * Patients under anticoagulant therapy. * Patients under bisphosphonates. * Pregnant and lactating women

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Conditions

The condition(s) this trial relates to.

injury periodontitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Bone regeneration Wound healing

Contacts and locations

Locations

  • Krishnadevaraya college of dental sciences and hospital

    Bangalore, Karnataka, 562157, India

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