Cure My Disease

Don't miss your cure!

 Log in / Sign up

Blood tests may reveal hidden healing power of bone marrow stem cells

NCT ID NCT07802106

Knowledge-focused Sponsor: Universidade Sao Francisco Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 03, 2026 · Last updated Sep 04, 2026 · Updated 1 time

Summary

Researchers are testing whether standard blood tests can indicate the quality of stem cells taken from the heel bone during foot or ankle surgery. The study includes adults aged 40 to 80, some with type 2 diabetes and diabetic foot ulcers. Before surgery, participants give blood samples; during surgery, a small amount of bone marrow is collected. Scientists then measure how well the stem cells grow and develop, and compare that with blood test results. The goal is to see if a simple blood test could help predict healing potential, though this study will not change individual treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
No intervention; observational study collecting blood samples and bone marrow aspirate during surgery
What this could lead to
If routine blood tests can indicate stem cell quality, doctors might better predict healing potential in patients with diabetic foot ulcers, possibly guiding future treatments.
What could go wrong
This is a small, exploratory study. The link between blood markers and stem cell function may not be strong or may not apply to broader populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Sep 2026

An estimate. Start dates often move.

Expected to finish

Jun 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults aged 40 to 80 years undergoing clinically indicated foot or ankle surgery at a university hospital in Brazil. Participants may have comorbidities, including type 2 diabetes mellitus and, when present, active Wagner grade 2-4 diabetic foot ulcers. All participants will undergo standardized preoperative blood collection and intraoperative calcaneal bone marrow aspirate collection for observational laboratory analyses.

Ages

40 to 80 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * Age 40 to 80 years. * Scheduled for clinically indicated foot or ankle surgery at the participating university hospital. * Ability to understand the study procedures and provide written informed consent. * Willingness to provide preoperative blood samples and intraoperative calcaneal bone marrow aspirate according to the study protocol. * Participants may have comorbidities, including type 2 diabetes mellitus and, when present, active Wagner grade 2-4 diabetic foot ulcers. These clinical characteristics will be recorded for observational analyses and do not define separate study groups. Exclusion Criteria * Critical limb ischemia without revascularization options or hemodynamic instability. * Active systemic infection or sepsis at the time of enrollment. * End-stage renal disease requiring dialysis. * Current use of high-dose systemic corticosteroids or other immunosuppressive drugs. * Current or recent malignancy within the last 5 years, except adequately treated non-melanoma skin cancer. * Significant cognitive impairment or psychiatric condition that, in the opinion of the investigator, precludes informed consent or adherence to study procedures. * Pregnancy or breastfeeding.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Diabetes mellitus, type 2 are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Diabetic Foot Inflammation injury type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Diabetes mellitus, type 2 Diabetic foot ulcer Foot ulcer due to type 2 diabetes mellitus Wound healing

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Leonardo H Dalcheco Messias

    Bragança Paulista, São Paulo, 12916900, Brazil

More trials for these conditions

Other studies related to the condition(s) this trial covers.