DIABETIC FOOT ULCER

This study tests whether a gel called NeoThelium FT, used with standard wound care, helps heal diabetic foot ulcers better than standard care alone. About 132 adults with diabetes and a foot ulcer that has lasted at least 4 weeks will take part. The main goal is to see if the ulc…

This study tests whether adding a special wound dressing called Omeza Complete Matrix to standard care helps heal chronic diabetic foot ulcers better than standard care alone. About 130 adults with diabetes and a foot ulcer that has not healed for at least 4 weeks will take part.…

This study is testing a borate-based bioactive glass fiber matrix, a special dressing that releases minerals to help heal wounds, in people with diabetes who have foot ulcers and a bone infection. Researchers will watch 20 patients to see if the glass helps the wound close comple…

This study tests whether adding a special amniotic membrane graft (Orion™) to standard wound care helps diabetic foot ulcers heal faster in people aged 50-85. About 240 participants will be split into two groups: one gets standard care alone, the other gets standard care plus the…

This study tests whether a special placental graft, used alongside standard wound care, helps close diabetic foot ulcers that won't heal on their own. About 350 adults with type 1 or 2 diabetes and a foot ulcer between 1 and 15 cm² will be randomly assigned to get the graft plus …

This study tests whether negative pressure wound therapy (a vacuum device) works better than standard wound care for diabetic foot ulcers. Fifty adults with diabetic foot ulcers needing surgery will be randomly assigned to one of the two treatments. Researchers will track amputat…

This Phase 2 study tests a topical gel called BB-101 for treating diabetic lower leg and foot ulcers. About 96 adults with diabetes will be randomly assigned to receive either the gel or a placebo, and neither they nor their doctors will know which they get. The main goal is to s…

This study compares two types of skin grafts (PelloGraft and SanoGraft) to standard wound care for healing diabetic foot ulcers and venous leg ulcers. About 180 adults with chronic wounds will be enrolled. The goal is to see if these grafts help wounds close completely within 12 …

This study is testing a special skin graft called NeoThelium FT to see if it can help heal diabetic foot ulcers. The study will include 10 adults with diabetes who have a foot wound that is not infected. The main goal is to see if the wound closes completely and stays closed for …

This study tests a portable device that uses red/near-infrared light and low-frequency magnetic pulses to help heal diabetic foot ulcers that haven't responded to standard care. About 450 adults with such ulcers will either receive the active device or a sham device, alongside us…

This study tests whether a special graft made from donated placental tissue, called XWRAP, can help heal diabetic foot ulcers that won't close with standard care alone. About 60 adults with type 1 or type 2 diabetes will receive either the graft plus standard wound care or standa…

This study tests whether special wraps made from human placental membrane can help heal diabetic foot ulcers and venous leg ulcers that won't close on their own. About 50 adults with diabetes or venous disease will receive weekly applications of one of four placental membrane pro…

This study tests whether a new wound dressing helps diabetic foot ulcers heal faster and safer than standard NHS care. About 100 adults with diabetes and a foot ulcer will be randomly assigned to get either the new dressing or usual care. The main goal is to see if the wound full…

This study tests whether using special gait analysis software and custom shoe inserts (orthotics) can help people with a history of diabetic foot ulcers avoid new ulcers and amputations. Researchers will analyze how participants walk and fit them with corrective orthotics. The go…

This study is testing a special soft cast for people with diabetic foot ulcers. The cast is a multi-layer wrap that cushions the foot and leg to help the wound heal. Researchers want to see if it works well, is comfortable, and safe. About 100 adults with diabetic foot ulcers wil…

This study tests whether a special dressing called EDX110, when added to standard care, helps diabetic foot ulcers heal faster and more completely. About 298 adults with a non-healing foot ulcer will be randomly assigned to receive either standard care alone or standard care plus…

This study tests a program called CARE-D-Foot-Nav, where a diabetes educator acts as a personal navigator for people with diabetic foot ulcers. The navigator helps with blood sugar control, wound care, transportation, and emotional support. Researchers want to see if this extra h…

This study tests whether a patch made from donated human placenta tissue, used alongside standard wound care, can help close diabetic foot ulcers better than standard care alone. About 120 adults with diabetes and a foot ulcer that hasn't healed for at least 4 weeks will take par…

This Phase 3 study tests whether a gel called ENERGI-F703 can help close diabetic foot ulcers better than a placebo gel. About 230 adults with diabetes and a foot ulcer that hasn't healed for at least 4 weeks will receive either the active gel or a placebo, along with standard wo…

This study tests if special sensor-equipped insoles can help prevent foot ulcers from coming back in people with diabetes and nerve damage. About 400 high-risk participants will use the insoles alongside standard care or just standard care alone. The goal is to see if the insoles…

This study is testing whether a medically supervised exercise program can help heal foot ulcers in people with type 2 diabetes. Sixty participants will do 2-3 exercise sessions per week for 12 weeks. The main goal is to see if exercise reduces the time it takes for the wound to c…

This early study is testing a mineral-based spray called THERAVEX on 26 people with various wounds, including burns, pressure sores, and diabetic ulcers. The spray is used alongside standard wound care to see if it helps the skin heal better and faster. So far, it appears safe an…

This early-stage study tests a topical spray called ELU42 on 15 adults with diabetic foot ulcers (Wagner grade 1-2) that have lasted 4 to 52 weeks. The spray is applied three times a week for six weeks. The main goals are to check safety and measure how much the wound shrinks. Th…

This study tests three types of diabetic boots to see which helps people with foot ulcers heal best. Some boots give reminders through a smartwatch to encourage wearing them as directed. The goal is to improve healing, sleep, and quality of life for 210 adults with diabetes.

This study is testing a device called FlowOx that uses gentle, intermittent suction (negative pressure) on the foot to improve blood flow and help heal diabetic foot ulcers. Thirty adults with diabetes and chronic foot wounds will use the device for one hour, twice a day for 12 w…

This study will give 100 adults with diabetes a thermal camera that attaches to their smartphone to take daily pictures of their feet. The goal is to collect temperature data and see if hot spots can predict where foot ulcers might form. Participants will use the device at home f…

This study follows 50 people whose diabetic foot ulcers healed in a previous trial. They will use a BlueDrop foot scanner at home each morning to take photos and thermal images, which are sent to a nurse. The goal is to see how often the ulcers come back and whether remote monito…

This study follows 1,000 adults with diabetic foot ulcers for up to 5 years to learn why some have worse outcomes, including death. Researchers will track health events and build a risk score to identify those most at risk. The goal is to better understand the disease and improve…

This study is collecting information from 200 patients with diabetic foot ulcers admitted to 5 Azar Hospital in 2024. Researchers will analyze blood tests and other data to see how they relate to ulcer severity. The goal is to find patterns that could help doctors prevent and man…

This study aims to find biological markers (biomarkers) that can predict whether a diabetic foot ulcer will heal or not. Researchers will collect samples like blood and wound fluid from 5,000 adults with diabetes and open foot ulcers. The goal is to develop a tool that helps doct…