DIABETIC FOOT ULCER

This study tested whether a medical device called OptiPulse helps heal diabetic foot ulcers better than standard wound care. Researchers compared the two approaches in 162 adults with foot ulcers that hadn't healed for at least 4 weeks. The device is designed to improve blood flo…

This study compared two different wound dressings for treating diabetic foot ulcers. 148 adults with diabetes and a foot ulcer that had been present for at least 4 weeks were randomly assigned to receive either a new borate-based glass fiber dressing or a standard calcium alginat…

This study tested whether a special dressing made from a patient's own blood (platelet-rich plasma) works better than a standard saline dressing for healing chronic skin sores that won't close on their own. It involved 100 adults with ulcers lasting over 6 weeks, including diabet…

This study tested a new treatment called ALLO-ASC-DFU, which is a sheet made from donor cells, to see if it could help heal foot ulcers in people with diabetes. It was compared to a placebo sheet in 104 patients with ulcers that had not healed for over 4 weeks. The main goal was …

This study tested whether adding a patient's own specially treated skin cells to a standard skin graft could help heal stubborn diabetic foot ulcers faster and better. It involved 108 adults with diabetes who had non-healing foot wounds. Researchers randomly assigned patients to …

This trial tested whether a new minor procedure called the 'inforatio technique' could help diabetic foot ulcers heal faster. One hundred patients with these hard-to-heal sores were randomly assigned to receive either standard wound care alone or standard care plus this new techn…

This small, completed study tested a new type of dressing designed to reduce pressure on foot ulcers in people with diabetes. 40 participants with foot ulcers wore a removable boot and were randomly assigned to receive either the new 'minimal offloading dressing' or a standard fe…

This study tested if adding a new topical gel called PEP-TISSEEL to standard wound care could help heal diabetic foot ulcers better than standard care alone. It involved 59 adults with a specific type of non-healing foot ulcer. Researchers compared the two treatment groups to see…

This study tested if using video calls with specialists could get faster care for people in rural areas with serious foot sores from diabetes and poor blood flow. Researchers compared patients who had video consultations to those who had to travel for standard in-person visits. T…

This study tested whether a new topical treatment called AUP1602-C could help heal chronic diabetic foot ulcers that weren't responding to standard care. 64 patients with these stubborn wounds were randomly assigned to receive either the new treatment or a placebo gel, in additio…

This study tested whether a new transforming powder dressing could heal diabetic foot ulcers better than standard wound dressings. 135 adults with a diabetic foot sore that had been present for at least a month were randomly assigned to use either the new powder or standard care.…

This study tested whether a new wound treatment called Symphony helps heal chronic diabetic foot ulcers better than standard care. 143 adults with foot ulcers that hadn't healed for over 4 weeks received either the Symphony treatment or standard wound dressings for 12 weeks. Rese…

This study tested if a special light treatment, called antimicrobial photodynamic therapy (aPDT), helps heal diabetic foot ulcers better than standard care alone. It involved 94 people with diabetic foot wounds. One group received the light therapy along with standard wound care,…

This study tested whether a portable oxygen therapy device could help heal chronic foot ulcers in people with diabetes. 73 participants used either the real oxygen device or a look-alike sham device at home for 90 minutes a day, five days a week, for up to 12 weeks. The main goal…

This study observed 35 people with diabetes who had serious foot ulcers and were at risk of amputation. Researchers tracked whether taking specific daily dietary supplements helped their wounds fully heal and prevented the need for foot or leg amputation. The study monitored pati…

This study tested whether adding a special graft made from donated placental tissue (called BR-AC) to standard wound care could help heal diabetic foot ulcers better than standard care alone. It involved 71 adults with a chronic foot ulcer that had not healed for over a month. Pa…

This study tested a skin substitute called Restrata Wound Matrix to help heal diabetic foot ulcers. Thirty adults with long-standing foot sores that hadn't responded to standard care received the treatment over 14 weeks. Researchers measured how many wounds completely closed and …

This study tested whether applying ozone gas directly to diabetic foot ulcers helps them heal better than standard wound care alone. Researchers enrolled 430 people with diabetic foot ulcers in Indonesia. One group received topical ozone therapy along with standard care, while th…

This study tested a new, faster method to identify the specific bacteria causing infections in diabetic foot ulcers. Researchers compared the new test to standard lab cultures in 44 participants to see if getting results quicker could help doctors choose the best antibiotics soon…

This study aimed to find the best simple bedside test for detecting poor leg circulation (peripheral arterial disease) in people with diabetes. Researchers compared several quick tests, like blood pressure measurements in the ankle and toe, against more complex imaging scans. The…

This study tested whether a personalized package of custom shoe inserts and foot care could prevent painful foot ulcers from returning in people with diabetes. It involved 126 adults with diabetes who had previously healed a foot ulcer. Researchers compared the new personalized a…

This study tested whether people at high risk for diabetic foot ulcers would regularly use a special smart mat at home. The mat checks foot temperature daily to spot early warning signs of a sore forming. Researchers followed 20 participants for six months to see how often they u…

This study aimed to understand how environmental factors and lifestyle choices affect the development, severity, and recurrence of diabetic foot ulcers. Researchers surveyed 179 adults in England who have diabetes and have experienced foot ulcers, asking about their jobs, quality…

This study aimed to find the best shoe fit guideline to reduce harmful pressure on the feet of people with diabetes and nerve damage. Researchers measured foot pressure and temperature in 60 participants while they walked in different specially-fitted shoes. The goal was to gathe…

This study looked back at the medical records of 160 people who had diabetic foot ulcers and were in a previous trial. The goal was to compare the total medical costs and amputation rates between two different wound treatments: a new cream called ON101 and a standard dressing cal…

This small pilot study aimed to see if a synthetic wound dressing called PHOENIX changes the types of bacteria and fungi living in chronic diabetic foot ulcers. Researchers enrolled 11 adults with diabetes and a foot ulcer that hadn't healed for at least 4 weeks. They collected w…