New DNA test could speed up infection treatment for diabetic foot ulcers

NCT ID NCT06569238

Completed Knowledge-focused Sponsor: University of Michigan Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether a rapid DNA sequencing method (mNGS) could better identify bacteria in diabetic foot ulcers compared to standard lab cultures. 44 adults with diabetes and an infected foot ulcer had tissue samples analyzed using both methods. The goal was to see if this faster diagnosis could help doctors choose the right antibiotics more quickly and improve wound healing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to faster, more targeted antibiotic treatment for diabetic foot ulcers, potentially improving healing.
What could go wrong: This was a small, completed study that only tested a diagnostic method, not a treatment. The results may not change patient outcomes or be widely applicable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

diabetes mellitus Diabetic Foot injury Wound Infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES MELLITUS DIABETIC FOOT ULCER WOUND

Contacts and locations

Locations

University of Michigan

Ann Arbor, Michigan, 48106, United States
University of Michigan

Ann Arbor, Michigan, 48109, United States

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