Can community hospitals in zambia master severe disease care?

NCT ID NCT07753681

First seen Aug 07, 2026 ยท Last updated Aug 07, 2026

Summary

This trial tests a new model of care called PEN-Plus, which brings specialized treatment for severe chronic diseases like diabetes, heart conditions, and sickle cell disease to first-level hospitals in Zambia. The goal is to train local health workers and set up clinics to manage these complex conditions closer to home. The study will see if this approach increases the number of patients diagnosed and treated effectively.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
Supportive treatment including insulin, hydroxyurea, and clinic/training center setup
What this could lead to
If successful, this could expand access to life-saving care for severe chronic diseases in low-resource settings, potentially improving outcomes for thousands.
What could go wrong
The trial is early and focuses on implementation, so benefits may vary. Challenges like drug supply and training could limit impact.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Matero First Level Hospital

    RECRUITING

    Lusaka, Lusaka Province, 10101, Zambia

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Other studies related to the condition(s) this trial covers.