CANCER

This study is testing two experimental procedures to help men regain their fertility. It is for men who froze a small piece of testicular tissue before undergoing treatments like chemotherapy that can cause permanent infertility. Researchers will either inject the stored cells ba…

This study is testing a new personalized treatment for adults with advanced solid tumors that have returned or stopped responding to standard therapies. Doctors take a patient's own immune cells, modify them in a lab to better target their cancer, and then infuse them back. The t…

This study is testing a new smartphone app designed to help people with cancer take their oral medication correctly. The app tracks pill-taking, monitors symptoms, and connects patients with support for side effects and costs. Researchers are enrolling 35 English- or Spanish-spea…

This study is testing a new type of cell therapy for people with advanced solid tumors that have stopped responding to standard treatments. Doctors will analyze a patient's tumor to select a specific target, then infuse specially engineered immune cells (CAR-NK cells) from a heal…

This is the first-ever study in people for a new drug called IMC-P115C, designed to treat advanced cancers that have a specific marker called PRAME. The main goal is to test the drug's safety and see if it causes any serious side effects when given alone or with standard treatmen…

This early-stage study is testing whether using high-intensity focused ultrasound to break apart a tumor can make immunotherapy drugs work better for people with advanced cancer that has stopped responding to standard treatments. The trial will enroll 24 adults to receive one ult…

This study aims to develop and test support strategies to help people in Zimbabwe who have both HIV and cancer stay engaged in their HIV care while undergoing cancer treatment. Researchers will first observe 150 patients to identify barriers, then create support strategies with e…

This study is testing whether giving radiation treatment a second time is safe for women whose breast cancer has returned in the same breast. Researchers want to understand both the benefits and risks of this approach for patients who have already had radiation therapy. The study…

This study allows cancer patients who were in previous Roche-sponsored trials to continue receiving their experimental treatments if they can't access them locally. It's for people who are still benefiting from the treatment and need ongoing therapy. The main goals are to provide…

This trial is testing if a drug called alectinib, already approved for a type of lung cancer, can help treat other rare cancers that share the same genetic change (ALK mutation). It will involve about 30 adults and children with various rare or hard-to-treat cancers. The goal is …

This study is testing a telehealth program designed to help young cancer patients access fertility preservation services. It aims to see if the program helps more patients get the fertility care that matches their personal goals and reduces the stress of making these decisions. T…

This trial is testing if a drug called capmatinib, already used for some lung cancers, can help adults with rare or uncommon cancers that have specific changes in a gene called MET. The goal is to see if the drug shrinks tumors or provides long-term benefit for these hard-to-trea…

This study tracks the long-term safety of nivolumab (Opdivo) cancer treatments for patients who previously participated in Bristol-Myers Squibb trials. It allows 1,500 cancer patients who responded well to continue receiving treatment while researchers monitor for any side effect…

This early-stage study is testing a new drug called MBRC-101 in adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find a safe and effective dose and to see if the drug can help control the cancer. The study will first tes…

This study aims to collect real-world information on proton therapy, a type of radiation treatment for cancer that may cause fewer side effects than standard radiation. It will enroll 500 adults with solid tumors who are candidates for this treatment in Italy. The main goal is to…

This study is testing a new talk therapy program designed to help cancer patients who are taking opioid pain medication. The goal is to see if the therapy is practical and acceptable for patients, and if it can help reduce risky opioid use and improve mental health. About 40 adul…

This is the first study in people to test a new oral medication called CID-078 for advanced solid tumors. The main goals are to find a safe dose and see how well the body handles the drug. The study will enroll adults with cancers like triple-negative breast cancer, small cell lu…

This study is for people who have seizures because of a brain tumor. Researchers want to see if surgery to remove the tumor can also reduce or stop the seizures. Participants will have the surgery and then be followed for several months to track their seizure activity, quality of…

This study is testing a new combination treatment for cancer that has spread to the liver. It combines a standard procedure (TACE) that delivers chemotherapy directly to the liver tumor with an added drug (bevacizumab) that aims to starve the tumor by blocking its blood supply. T…

This study is testing whether combining two drugs, nab-sirolimus (given by IV) and letrozole (a daily pill), can help control advanced or recurrent endometrial cancer. It is for patients whose cancer has returned or spread and who have had zero to one prior rounds of chemotherapy…

This study offers an experimental procedure to freeze testicular tissue from boys who are about to undergo treatments (like chemotherapy) that will likely make them infertile. The goal is to preserve the tissue so that, if future scientific advances allow, it could potentially be…

This study is testing if a lower, gentler dose of steroids can safely treat liver inflammation that sometimes occurs as a side effect of powerful cancer immunotherapies. It will involve about 63 adult cancer patients who develop this specific liver issue. The goal is to see if th…

This study is testing a patient navigation program designed to help people with cancer or suspicious screening results get better access to care and support. It focuses specifically on Black, Hispanic, and residents of high-need areas in Cleveland. The goal is to see if having a …

This study is gathering information on a computer-assisted procedure to remove dangerous blood clots from the lungs of cancer patients. It aims to see if the procedure is safe and if it helps patients feel better and breathe easier. The study will follow 25 adult cancer patients …

This study is testing whether adding short, high-dose bursts of targeted radiation to standard immunotherapy helps control advanced solid tumors better. It will involve about 35 people already receiving immunotherapy. Researchers will compare the new combination to standard treat…

This trial is testing if an existing immunotherapy drug called atezolizumab can help control rare cancers or common cancers with rare genetic features. It will involve about 30 adults and children whose cancers have specific genetic markers. The goal is to see if this approved dr…

This study allows cancer patients who were already receiving darolutamide in a previous Bayer-sponsored trial and are benefiting from it to continue treatment. It aims to provide continued access to the medication while closely monitoring for any side effects or safety issues. Ab…

This study is testing a new support program for cancer survivors who struggle to afford or access healthy food. Researchers will compare 100 patients who receive help from a patient navigator to those getting standard care, to see if the program improves food security, diet quali…

This study is tracking 3000 cancer patients who take their anticancer pills at home instead of receiving injections in the hospital. Researchers want to see if a special support program helps patients take the right dose safely and avoid problems. The goal is to improve how docto…

This early-stage trial is testing a new drug called TTX-080, both alone and combined with other cancer therapies, for people with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find safe doses and see if the drug shows any signs o…

This study is testing if a medicine called tranexamic acid, breathed in as a mist, can help control life-threatening lung bleeding in cancer patients who are on a breathing machine. It will compare this inhaled treatment to standard care to see if it improves survival at 28 days …

This study is testing an experimental therapy called RP1 for people who have had an organ or bone marrow transplant and now have advanced skin cancer. RP1 is a modified cold sore virus that is injected directly into tumors to try to destroy them and boost the body's immune respon…

This study is testing a new patient-centered care model called FRAME, designed to help cancer survivors manage long-term side effects after their main treatment ends. It involves patients filling out a questionnaire about their needs before a clinic visit, then having a focused c…

This is the first study in people testing a new cancer drug called AGX101. It aims to find a safe and effective dose for patients with advanced solid tumors that have spread or cannot be removed by surgery, and who have no other standard treatment options left. The drug is given …

This study is testing whether a drug called larotrectinib can make radioactive iodine treatment more effective for people with advanced thyroid cancer that has spread to the lungs. Participants will take larotrectinib for six months, then receive standard radioactive iodine thera…

This is the first time a new drug called IMA401 is being tested in people. The main goal is to find a safe dose and see if it can help control advanced solid tumors that have come back or stopped responding to other treatments. The study will test IMA401 by itself and combined wi…

This study is testing a new nutrition and exercise program designed for cancer survivors who are overweight or obese. The goal is to find the best combination of support—like one-on-one counseling, group sessions, and skill-building—to help participants manage their weight and im…

This early-stage trial is testing a new oral drug called ALTA2618 for people with advanced cancers that have a specific genetic mutation called AKT1 E17K. The study aims to find the safest and most effective dose and see how well the drug works against cancers like breast and end…

This trial is testing if a drug called entrectinib, already approved for some lung cancers, can help control other rare cancers that share the same genetic change (called ROS1-positive). It aims to enroll about 30 adults and children with these rare cancers to see if the drug shr…

This study is testing an oral drug called zotiraciclib for people whose aggressive brain tumors (gliomas) have come back after prior treatment. It is specifically for patients whose tumors have certain genetic changes (IDH1 or IDH2 mutations). The main goals are to find a safe do…

This study is testing whether a simple text-message system can help cancer survivors who have symptoms of depression get connected to mental health care. The goal is to see if this approach is easy to use and helpful for patients. Researchers will enroll 60 adult cancer survivors…

This study is testing a new interactive story app that uses artificial intelligence to help teenagers reduce risky alcohol use. The app, called CHANGEGRADIENTS, creates personalized stories where teens can explore the consequences of their choices in a virtual environment. Resear…

This early-stage trial is testing a new drug called FOG-001 for people with advanced or spreading cancers that have specific genetic mutations. Researchers want to find the safest dose and see if the drug can shrink tumors or slow cancer growth. The study will include 575 partici…

This study is testing if changing the order of breast cancer treatments improves how women feel about their bodies after surgery. It compares giving radiation therapy before breast removal and reconstruction (the new approach) to the standard method of radiation after surgery. Th…

This study is testing whether a drug called abatacept can reduce serious heart complications in people who develop heart inflammation (myocarditis) as a side effect of immune-based cancer treatments. It will involve 390 hospitalized patients who are already receiving standard ste…

This study is testing a new type of immune therapy drug called IMC-R117C for people with advanced colorectal, esophageal, gastric, or ovarian cancers. The drug is designed to help the body's own immune cells find and attack cancer cells. Researchers will test the drug alone and i…

This Florida-based study is testing a new AI-powered approach to find personalized treatments for cancer patients whose disease has returned or stopped responding to standard therapies. It aims to serve 210 patients, with a special focus on reaching children and underserved commu…

This study aims to see if a new drug called DWZ2501 behaves the same way in the body as an existing drug (DWC202510) for patients with advanced ovarian cancer linked to a BRCA gene change. It will involve about 40 women who are already taking or need to start the existing drug. T…

This is a first-in-human study to test a new investigational drug called SYS6043 in adults with advanced or metastatic solid tumors that have spread or no longer respond to standard therapies. The main goals are to find a safe dose, understand the drug's side effects, and see how…

This study is testing a new support program for young women who have survived cancer and live in rural areas. The program aims to help them get the reproductive healthcare they want, whether it's related to fertility, birth control, or other needs. Researchers will work with 64 p…

This study is testing whether digital tools like text message reminders and online resources can help young adults who survived childhood cancer return to important long-term follow-up doctor visits. Researchers want to see which combination of reminders and support works best to…

This study is testing whether a 6-month telehealth program using smartphones can help cancer survivors prevent painful mouth sores and gum disease, improve their quality of life, and reduce body-wide inflammation. It will compare this program to usual care in 100 cancer survivors…

This program provides access to an experimental drug called AVM0703 for patients with various solid tumors and blood cancers. It is for people who may not have other treatment options. The drug aims to help the body's immune system fight cancer, and early reports show mostly mild…

This study aims to preserve fertility for girls and women under 40 who face cancer treatments or other conditions that could cause permanent infertility. Participants have one ovary surgically removed and frozen for potential future use when they wish to have children. The resear…

This is a first-in-human study to test the safety and find the right dose of a new experimental drug called CPO301 in adults with advanced or metastatic solid tumors that have stopped responding to standard treatments. The drug is designed to target and deliver a toxic payload sp…

This study is testing whether video consultations with geriatric and pharmacy specialists can improve care for cancer patients aged 75 and older who live far from major hospitals. It aims to see if this remote support helps reduce unexpected trips back to the hospital and better …

This program provides access to an investigational oral drug called sevabertinib for adults with advanced non-small cell lung cancer that has a specific genetic mutation (HER2). It's designed for people whose cancer has progressed after at least one prior treatment and who have n…

This is an early-stage study to see if a new cell therapy called XJ-MK-002 is safe and can help raise platelet counts. The therapy involves a single injection of cells derived from umbilical cord blood. Researchers will test three different doses in a small group of adult cancer …

This is a very early study to check the safety and initial signs of effectiveness of a new drug called WTX212A. It will be given to 12 adults with advanced solid tumors, either by itself or combined with radiation therapy. The main goals are to see if the treatment is safe and ho…

This study is testing a new type of treatment called EBNK-001, which uses donated immune cells (Natural Killer cells) to fight cancer. It is for adults with advanced solid tumors that have grown or returned after standard treatments. The main goals are to find a safe dose and see…

This is an early-stage study testing a new drug called JMT108 in adults with advanced solid tumors that have not responded to standard treatments. The main goals are to find a safe dose and see if the drug shows any early signs of helping to shrink tumors. Participants will recei…

This study is testing whether a personalized support program helps smokers who have cancer quit. About 1,450 participants in Hong Kong will either get brief advice to quit immediately or get to choose their own quit date and receive encouraging text messages for 6 months. The goa…

This study is testing a new self-help booklet designed to increase motivation to quit smoking in people recently diagnosed with specific cancers. Researchers want to see if the booklet is practical for patients to use and if they find it helpful. The study will also track if part…

This study is testing whether some multiple myeloma patients who are in a very deep, sustained remission can safely stop their long-term maintenance therapy. It will enroll about 70 patients who have been on therapy for at least two years and have no signs of cancer in very sensi…

This study is testing a new type of cell therapy called A2B395 for adults with advanced solid tumors that have spread or returned. The therapy uses modified immune cells designed to specifically kill cancer cells while protecting the patient's healthy cells. The main goals are to…

This study is testing if adding a special breathing muscle trainer to standard pre-surgery exercise helps people with lung cancer. The goal is to make patients stronger for surgery, reduce complications like pneumonia, and shorten hospital stays. Researchers will compare two grou…

This early-stage study is testing a new cancer drug called INV-1120, both by itself and combined with an existing immunotherapy (pembrolizumab), in adults with advanced solid tumors that have stopped responding to standard treatments. The main goals are to find safe dose levels a…

This study is testing whether combining a short, intense course of targeted radiation with immunotherapy drugs can better control advanced cancers that have spread. It is for adults with metastatic liver, kidney, or bladder cancer who have up to 10 tumor sites. The main goal is t…

This trial is testing a new, first-of-its-kind drug called IMA402 in adults with advanced solid tumors that have come back or stopped responding to all standard treatments. The main goals are to find a safe dose and see if the drug can shrink tumors. The study will enroll about 1…

This study aims to improve safety for cancer patients receiving targeted radiation therapy by having pharmacists review all their medications. Researchers will enroll 600 adults with thyroid cancer, prostate cancer, or neuroendocrine tumors to test whether detailed medication rev…

This study is testing a lower-dose version of a three-drug combination (isatuximab, lenalidomide, and dexamethasone) for people newly diagnosed with multiple myeloma who are older or frail. The goal is to see if using lower doses can effectively control the cancer while causing f…

This study freezes ovarian tissue from women and girls (ages 0-45) who are at high risk of losing their fertility due to medical treatments like chemotherapy or surgery. The goal is to preserve the tissue so that in the future, the immature eggs might be matured in a lab or the t…

This study is testing whether taking maitake mushroom supplements alongside standard cancer treatments like chemotherapy can help improve patients' immune function and quality of life. Researchers will measure changes in blood cell counts, inflammation markers, and patient-report…

This study allows cancer patients who benefited from previous Eli Lilly drug trials to continue receiving the study medication after those trials conclude. It focuses on monitoring the long-term safety of these treatments. Only patients who were already receiving the drug in a co…

This study is testing whether the drug abemaciclib can slow or stop the growth of advanced solid tumors that have specific genetic abnormalities. It is for adults with cancers that have mutations in certain genes (CCND1, CCND2, CCND3, CDK4, or CDK6) and for whom standard treatmen…

This study is testing a new support program to help cancer patients, especially older or frail ones, safely transition from the hospital back home. It involves a nurse consultation and a system where patients report their symptoms and well-being using a smartphone or tablet after…

This early-stage trial is testing a new oral medication called ALTA3263 in adults with advanced solid tumors that have specific KRAS mutations. The study aims to find a safe dose and see how the body processes the drug, while also checking for early signs that it might help contr…

This study is testing a special 6-month heart health program for young cancer survivors who are at risk for heart problems due to their past cancer treatments. The program combines supervised and home-based exercise with lifestyle coaching and is compared against standard advice.…

This study is testing whether a special diet and exercise program before cancer surgery is practical and helpful for American Indian patients. The 3-week program includes eating walnuts, walking daily, and supervised exercise sessions. Researchers will check if participants can s…

This study is testing a new type of personalized cell therapy for adults with advanced solid tumors that have come back or spread. The therapy, called Tmod CAR T, is designed to recognize and kill cancer cells while using a built-in safety switch to protect the patient's healthy …

This study is testing if a drug called selpercatinib can make a standard thyroid cancer treatment (radioactive iodine) work better for children and young adults. It focuses on patients aged 2-25 with a specific genetic change (RET fusion) in their cancer. The goal is to see if ta…

This program provides expanded access to personalized cancer vaccines for patients with solid tumors who have run out of standard treatment options. The vaccine is custom-made to target each patient's specific cancer markers. Eligible patients must have a poor long-term survival …

This study aims to see if providing free healthy prepared meals and nutrition education improves people's diets more than just getting exercise coaching. It involves 120 adults from Anson County, NC, who have or are at risk for chronic conditions like diabetes or heart disease. P…

This study aims to find out if cancer survivors can safely stop taking heart failure medications after their heart function has returned to normal following cancer treatment side effects. Researchers will compare two groups: one that continues medications and one that stops them,…

This study is testing whether adding a new drug called azeliragon to a precise form of radiation therapy is safe and more effective at controlling brain tumors that have spread from other cancers. It will involve about 46 adult patients with small brain tumors. The main goal is t…

This study is testing whether a 12-month, phone-based weight management program can help young adult cancer survivors (ages 18-39) who have overweight or obesity. Participants are randomly assigned to either a guided program with personalized goals, digital tools, and peer suppor…

This is the first study in people to test a new drug called NTX-1088, an antibody designed to target a protein found on many cancer cells. The main goals are to find safe doses and see how the body processes the drug, both by itself and when combined with an existing immunotherap…

This is the first-ever study in people to test a new cancer drug called TT125-802. The main goal is to find a safe dose and check for side effects in 50 adults with advanced solid tumors that have stopped responding to standard treatments. Researchers will also look for early sig…

This study is looking back at past medical records to see how effective a tiny, swallowable camera (capsule endoscopy) is at finding early signs of cancer in the small intestine of people with Lynch syndrome. Lynch syndrome is a genetic condition that increases a person's risk fo…

This study is testing a new blood test designed to help doctors detect cancer in people who have symptoms that could be caused by cancer. Researchers will enroll 1,650 adults aged 45 and older who are already undergoing testing for suspected cancer. The goal is to see how accurat…

This study aims to see if a blood test called Galleri can help find cancer earlier in people aged 50 and older on Medicare. It will enroll 50,000 people and compare outcomes between those who get the test plus usual care and those who get usual care alone. The main goal is to see…

This study is testing whether analyzing DNA and proteins in urine can help detect cancers of the bladder and kidney. Researchers will compare this new, non-invasive method to current standard procedures like cystoscopy. The goal is to develop a simpler, more comfortable way to fi…

This study is testing a new high-resolution PET-CT scanner designed to help surgeons see cancer margins during surgery. After a tumor is removed, the device scans it in the operating room to check if all cancerous tissue was taken out. The goal is to see if this real-time imaging…

This study aims to find the best way to screen firefighters for cancer early, as their job puts them at higher risk. It will test three different screening tools—whole-body MRI, whole-body ultrasound, and a special blood test—on 800 active firefighters. The goal is to see how wel…

This study is observing whether a new, high-resolution PET-CT scan of a tumor immediately after it's removed can help surgeons and doctors. The goal is to see if the scan's images match the lab results and if using this information during surgery leads to better long-term outcome…

This study is testing a new way to screen for depression in people who have survived cancer. Researchers want to see if sending a short depression questionnaire via text message before a doctor's appointment is a practical and acceptable method. They will compare this text-based …

This study is testing a new screening questionnaire to see if it can better identify cancer survivors who need occupational therapy. Researchers will compare the new tool to the current standard used in a rehabilitation clinic. The goal is to make sure survivors who struggle with…

This study is testing a new artificial intelligence (AI) tool designed to help doctors detect when cancer has spread to a patient's lymph nodes. It will compare the AI's accuracy against standard pathology reports from doctors. The goal is to see if the AI can make the diagnostic…

This early-stage study is testing a new imaging tracer called 64Cu-FBP8 to see if it can safely and accurately detect blood clots throughout the body using a PET-MR scan. Researchers are enrolling 165 healthy volunteers and patients with conditions like atrial fibrillation, COVID…

This study is testing a new diagnostic platform that uses artificial intelligence to analyze small pieces of a patient's tumor. The goal is to predict whether a patient's cancer will respond to immunotherapy drugs before they start treatment. Researchers will compare the AI's pre…

This study compares two standard procedures used to diagnose cancer when fluid builds up around the lungs. Researchers want to know if starting with a more invasive biopsy (pleuroscopy) leads to a faster diagnosis and quicker start of cancer treatment compared to starting with a …

This study is testing a new Spanish-language program called ProSalud, which aims to teach Latino parents in rural Florida about healthy habits to lower their family's cancer risk. Parents attend a workshop about nutrition, exercise, and sun safety, and some are later asked for fe…

This study aims to find the best way to use a common blood thinner (apixaban) to prevent dangerous blood clots in cancer patients who are at moderate risk. About 1,000 patients starting cancer treatment will be randomly assigned to take the standard twice-daily dose, a new once-d…

This study offers an experimental procedure to freeze and store testicular tissue from boys (ages 0-17) who are about to undergo cancer treatments like chemotherapy or radiation that have a high risk of causing permanent infertility. The goal is to preserve the tissue so it might…

This study aims to understand and reduce a person's risk of developing cancer. It will enroll 1,000 adults to track their health, lifestyle, and family history over time. The goal is to identify people at high risk and connect them with doctors for early screening and prevention …

This study is testing whether psilocybin (a compound found in 'magic mushrooms'), combined with psychotherapy, can help reduce depression and anxiety in people who have survived cancer. It will involve about 20 participants and aims to check if the treatment is safe and practical…

This study is testing a communication coaching program called COACH-Cog. It's designed to help older adults who have both dementia and cancer, along with their family caregivers, talk more effectively with their doctors about treatment choices. The goal is to make sure the patien…

This study is testing whether digital rehabilitation programs are practical and helpful for cancer patients. It involves 300 patients across five European countries who are either currently receiving treatment or have recently finished. The goal is to see if delivering physical t…

This study is testing a community-based program designed to help cancer survivors and their support people living in persistent poverty areas improve their health. The program focuses on adapting healthy eating and physical activity approaches to fit the specific challenges these…

This study is testing whether a mobile phone-based exercise program can help older adults with blood cancers maintain their physical strength and reduce fatigue during chemotherapy. Researchers will compare the exercise app against standard education materials in 170 participants…

This study aims to see if a 12-week digital, home-based resistance exercise program is as effective as the same program done in a supervised gym setting for people recovering from cancer treatment. It will enroll 120 participants to compare how well people stick to the program an…

This small pilot study is testing whether using virtual reality (VR) is a safe and helpful way to improve the mental well-being of cancer patients during treatment. Researchers want to see if relaxing VR experiences, like walking through a forest or swimming with dolphins, can re…

This study is testing a counseling program designed to help young adults with cancer and their caregiving partners cope better together. It involves eight therapy sessions based on proven methods, tailored for couples facing cancer. The main goal is to see if the program is pract…

This study explores whether a virtual group writing program can help young adult cancer survivors improve their quality of life. Researchers will work with 30 participants aged 18-39 who finished cancer treatment 1-5 years ago. The program involves four writing sessions designed …

This study aims to see if combining talk therapy (CBT) with light therapy, medication, or melatonin can help improve sleep quality, fatigue, anxiety, and depression in people with advanced cancer. Researchers will compare these active treatments against placebo (inactive) treatme…

This study is testing whether writing about personal experiences can improve quality of life and reduce stress for Asian American cancer survivors. Researchers will enroll 192 adults who have completed their primary cancer treatment within the last 5 years. Participants will writ…

This study is testing whether using a virtual reality (VR) headset during a single chemotherapy session can help reduce the distress, anxiety, and pain that often come with cancer treatment. 70 adult cancer patients will be randomly assigned to either use VR or choose a standard …

This study is testing a 6-month virtual program to help cancer survivors get and stay physically active. Researchers are comparing standard exercise advice with enhanced behavioral counseling to see which approach better helps people maintain activity levels and improve their qua…

This study is testing whether ustekinumab can help control severe diarrhea and colon inflammation that sometimes occurs as a side effect of cancer immunotherapy drugs. Researchers will give ustekinumab to 10 cancer patients experiencing these complications to see if it reduces sy…

This study is testing whether using the Calm meditation app for 10 minutes a day can help people with blood cancers who have trouble sleeping. Researchers will enroll 276 patients to see if the app improves sleep quality, reduces fatigue and anxiety, and lowers body inflammation …

This study is testing whether a 6-session video support program can help older adults who have cancer and mild memory problems, along with their spouse or caregiver. The program aims to reduce distress, improve communication, and enhance quality of life for both people in the pai…

This study aims to help Black women who have finished cancer treatment maintain physical activity habits. Researchers are testing if text message reminders, peer coaching, or a combination of both can help survivors overcome exercise barriers and stick with it. The goal is to imp…

This study is developing and testing a new virtual reality (VR) device designed to help people manage chronic cancer pain. The VR experience uses principles from cognitive behavioral therapy to distract from pain and lower pain sensations. Researchers will compare the VR device t…

This study is testing whether acupuncture is a practical way to help young women get their menstrual periods back after chemotherapy. Researchers will enroll 60 participants who lost their periods due to cancer treatment and randomly assign them to receive acupuncture or wait for…

This study aims to see if providing nutrition counseling and palliative care support can improve the quality of life, daily function, and nutritional health of cancer patients in Bangladesh. It will involve 215 patients who are receiving standard cancer treatment. Patients will b…

This small pilot study is testing whether a simple, daily 3-minute hand-held vibration therapy is safe and practical for reducing nerve pain in the hands caused by chemotherapy. Researchers want to see if this approach can ease symptoms and improve quality of life for cancer surv…

This study is testing a digital health program called AYA STEPS that helps young adult cancer survivors manage symptoms like pain, fatigue, and emotional distress. The program teaches skills to improve communication with healthcare providers and engagement with recommended follow…

This study aims to find the best way to help parents struggling with intense grief after losing a child to cancer. Researchers will compare three different types of support programs to see which one most effectively reduces symptoms of prolonged grief and depression. The study is…

This study is testing two different video-based support programs to see if they can improve psychological wellbeing and quality of life for people with advanced cancer and their family caregivers. Researchers will enroll 400 patient-caregiver pairs who are experiencing significan…

This study is testing if updated, clearer instructions help first-time radiation therapy patients. It will measure if better information helps patients complete their full treatment, miss fewer appointments, and feel more comfortable during the process. The goal is to find the be…

This study is testing whether watching virtual reality (VR) videos can help reduce anxiety and improve the overall experience for people receiving radiation therapy for cancer. Researchers will compare different VR experiences against a standard educational video to see which wor…

This study is testing a new smartphone app designed to help adolescent and young adult cancer survivors manage symptoms of depression. Researchers want to find out which parts of the app, or which combination of parts, are most helpful in reducing these symptoms. The study will i…

This study is testing whether providing specially tailored groceries, with or without nutrition counseling, helps people with cancer eat better and feel better. It will involve 100 adults in Maine who have been diagnosed with cancer, comparing three groups over six months. The ma…

This study is testing whether a digital avatar coach can help reduce anxiety and improve quality of life for cancer patients undergoing outpatient stem cell transplants. Researchers will compare the avatar-based support program against usual care for 90 patients. The goal is to h…

This study is testing if a special screening and referral program can help cancer patients get into exercise programs before they start treatment. Researchers want to see if this 'prehabilitation' helps people feel stronger, more active, and improves their overall quality of life…

This study is testing whether a 6-week online program of nature-based meditation recordings can help people who are grieving after caring for a family member or friend who died from cancer. Researchers want to see if the program is practical and helpful for reducing grief and imp…

This study tests whether magnetic stimulation of the brain can reduce chronic nerve pain in cancer patients. Sixty participants with pain that hasn't responded well to medications will receive either real or placebo brain stimulation sessions. Researchers will compare pain relief…

This study is testing whether a supervised, remote exercise program can reduce severe fatigue in young adults who have survived brain cancer. Researchers will enroll 75 survivors aged 18-39 who are struggling with fatigue and are less than five years out from treatment. The goal …

This study is testing whether a smartphone app can help cancer survivors who have trouble sleeping. The app delivers a proven talk therapy program for insomnia. Researchers will compare 146 participants who use the app right away to others who wait 8 weeks to see if it improves s…

This study is testing whether a virtual reality (VR) program used at home can help people manage common symptoms after cancer treatment, like pain, fatigue, anxiety, and trouble sleeping. It will compare the VR program to a similar audio-only program to see which is more helpful.…

This study is testing whether a more structured care plan can better manage symptoms and improve the care experience for adults with advanced cancer who are receiving outpatient palliative care. Researchers will compare a new structured approach, which uses specific patient-repor…

This study tests whether having cancer patients report symptoms from home using a digital system helps them feel better and reduces hospital visits. Patient navigators will help 7500 adults receiving cancer treatment use weekly symptom check-ins. The goal is to see if this real-w…

This study examines how well a medication called naldemedine works for cancer patients who experience constipation as a side effect of opioid pain medication. Researchers will follow 100 adult cancer patients in the Netherlands who are already using laxatives but still have signi…

This study is testing different combinations of cancer education, counseling, and peer support meetings designed specifically for Chinese cancer patients and survivors. Researchers want to see which combinations work best and are most practical for improving participants' quality…

This study is testing a free, 8-12 week exercise program designed specifically for people who have or have had cancer. The program offers twice-weekly supervised classes, either online or in-person, to help participants improve their fitness, manage cancer-related symptoms like f…

This large study is testing whether adding spiritual care from a chaplain or psychotherapy/meditation sessions to standard medical care helps people with advanced, incurable cancer live longer. It will also measure if these supportive services improve patients' quality of life an…

This study is testing whether early, personalized nutrition advice from a dietitian can help cancer patients receiving palliative chemotherapy. It aims to see if this support helps patients maintain their weight, improve their quality of life, better tolerate treatment, and poten…

This study is testing if a specific exercise and nutrition plan can help women with breast cancer feel better during chemotherapy. Researchers want to see if supervised weight training sessions, combined with a high-protein drink after each workout, can help patients keep their m…

This study is testing whether a 12-week stationary cycling program is a practical and acceptable way to help reduce nerve pain and numbness caused by chemotherapy. Researchers will recruit 30 adult cancer survivors with mild nerve symptoms to participate in twice-weekly, supervis…

This study is testing whether adding a specialized physiotherapist, called a navigator, to a cancer care team is practical and helpful. The navigator would check in regularly with patients during their cancer treatments to spot side effects early, help manage issues like fatigue,…

This study is testing whether a digital program delivered on phones or tablets can improve the overall health and well-being of people recently diagnosed with cancer. 440 participants will be randomly assigned to try one of two online courses and complete surveys and at-home bloo…

This study is testing whether a new smartphone app can help people better manage the side effects of chemotherapy. The app combines daily symptom check-ins with data from a Fitbit activity tracker. If the app detects concerning symptoms or health readings, it suggests when to con…

This study is testing a computer tool designed to help teenagers and young adults with cancer better manage their treatment symptoms. Researchers will compare the tool against standard care for 126 participants who are within their first three months of cancer diagnosis. The main…

This study is testing whether a therapy session using the psychedelic compound psilocybin (from 'magic mushrooms') can help reduce anxiety in people struggling to adjust to a cancer diagnosis. About 87 adults will receive one of three different doses of psilocybin during a guided…

This study is testing whether electroacupuncture—a form of acupuncture that uses mild electrical stimulation—can safely help reduce depression in people with cancer. Researchers will compare the treatment to a control group in 86 participants to see if it improves mood and qualit…

This study is testing whether using virtual reality (VR) headsets can help people with cancer manage their chronic pain. Researchers want to see if immersive, pleasant VR experiences can reduce pain and possibly lessen the need for opioid pain medications. They are recruiting 25 …

This study is testing whether psilocybin, the active compound in 'magic mushrooms,' can help reduce depression in adults who have both cancer and major depressive disorder. Fifty-six participants will receive either psilocybin or a placebo vitamin in group therapy sessions, with …

This study is testing whether an herbal formula called Ma-Zi-Ren-Wan (MZRW) can help relieve constipation in people who have survived cancer. Researchers will compare MZRW to a placebo (a dummy pill) over two weeks to see if it increases comfortable bowel movements. They will als…

This study is testing whether a combination of aromatherapy (smelling essential oils) and self-hypnosis can help improve comfort for cancer patients during stressful medical procedures like blood draws or dressing changes. It involves 66 adults receiving cancer care who will lear…

This study aims to find the most effective pain management approach for patients undergoing minimally invasive cancer surgery. Researchers will randomly assign 48 participants to one of three pain control methods used during their operation. The study will compare pain levels, me…

This study is testing whether a simple digital art activity helps adult cancer patients better express their symptoms and emotional distress. Researchers will compare the art activity to listening to music to see which helps patients communicate their experiences more openly. The…

This study tests whether group education sessions help veterans with cancer plan their future medical care better than standard mailed materials alone. 50 veterans with new cancer diagnoses will either receive mailed information or participate in two group sessions about care pla…

This study is developing and testing a short, 5-session support program designed to improve the emotional wellbeing and quality of life for people caring for a loved one with advanced cancer. Researchers want to learn what kind of support is most helpful for caregivers. The goal …

This study is testing a new program that provides legal help to cancer patients. It aims to see if helping patients with issues like insurance denials, disability benefits, and employment rules is practical and can reduce their stress and improve their quality of life. The progra…

This study is testing if a smartphone app called 'Moodivate' can help reduce depression in people living with incurable cancer. About 279 participants will be randomly chosen to either use the app or not for 12 weeks. The goal is to see if this easy-to-access digital tool can imp…

This early-stage study is testing whether fentanyl, a strong pain medication, can be safely delivered through an inhaler for cancer patients. It will compare how the body processes inhaled fentanyl versus the standard intravenous (IV) injection. The goal is to see if this new met…

This study is testing a coaching and navigation program called enCompass Humana, designed to support family members who are unpaid caregivers for adults with both cancer and diabetes. The goal is to see if the program is practical and acceptable, and if it can help caregivers fee…

This study is testing whether a smartphone app and smartwatch can help identify young people with cancer who are struggling with depression, anxiety, or stress. The goal is to use this digital information to connect them to mental health support faster. The pilot will involve abo…

This study is testing whether providing hearing aids can improve the quality of life for adult cancer patients. These patients have developed hearing loss or ringing in the ears (tinnitus) as a side effect of their platinum-based chemotherapy. Researchers will compare the well-be…

This study is testing two different exercise programs to help people with cancer feel better during treatment. Researchers will compare traditional flexi band resistance training to whole-body electrical muscle stimulation (EMS) over 12 weeks. They want to see which method better…

This study is testing a social support coaching program called SONATA to see if it helps older adults cope with cancer treatment. The program involves about six sessions over four months, where patients and their chosen support people learn to work together. Researchers want to s…

This study is testing whether a smartphone app can deliver art therapy to help young adults who survived childhood cancer. Fifteen participants aged 18-25 will use the app for six weeks, completing weekly art prompts and surveys about their mood. The main goal is to see if this d…

This study is testing whether a new 5-session phone therapy program called CARE can better help older adults with cancer who are feeling depressed or distressed. Researchers will compare CARE against standard supportive phone counseling to see which is more effective. The study i…

This study is testing whether a yoga program led by a trainer who shares the same racial background can improve quality of life and reduce symptoms for Black and African American cancer survivors. Researchers want to see if this culturally tailored approach makes the program more…

This study aims to develop and test a yoga therapy program designed to be culturally sensitive for cancer patients undergoing stem cell transplants. The program will be offered to 60 patients in the United States, India, and Tanzania to see if it helps reduce depression and stres…

This study is testing whether a smartphone app with an AI chatbot can help improve the well-being of people undergoing cancer treatment. Sixty participants receiving psychotherapy will be randomly assigned to either use the app alongside their usual therapy or receive therapy alo…

This study is testing whether group counseling can help people who feel shame or stigma because of their health condition. Researchers are enrolling 195 adults with conditions like obesity, cancer, HIV, diabetes, or chronic pain who report feeling stigmatized. Participants will t…

This study is testing whether a 4-week mindfulness app can help cancer survivors manage stress, anxiety, and fatigue after finishing their main cancer treatments. About 345 participants will either use the app right away or wait 3 months to use it, allowing researchers to compare…

This study is testing a new online group therapy program designed to help parents of childhood cancer survivors. The program aims to teach parents skills to manage the intense fear that their child's cancer might come back. Researchers want to see if the 7-week video call session…

This study is testing whether a writing program can help Chinese American cancer survivors feel better emotionally. Participants will write about their cancer experiences to see if it reduces depression, anxiety, and stress while improving quality of life. The research focuses sp…

This study is testing a specific nerve transfer surgery to see if it can improve facial movement and quality of life for head and neck cancer patients who have facial paralysis. Researchers will enroll 40 patients to measure changes in their facial function and daily life after t…

This study is testing an online self-management program designed to help Chinese cancer survivors who have a moderate fear of their cancer returning. The program, called eConquerFear-HK, teaches coping strategies and is being compared to a standard control activity. Researchers w…

This study is testing whether an online pain coping skills program helps cancer survivors manage persistent pain better than standard care alone. Researchers will enroll 456 adult cancer survivors who have pain that started or worsened after cancer diagnosis or treatment. Partici…

This study compares two ways nurses place IV drips for cancer treatment. One method uses touch and sight to find a vein, while the other uses a small ultrasound scanner to see the vein under the skin. Researchers want to know if ultrasound helps get the IV in successfully on the …

This study is testing whether a 'Dyadic Life Review' program, where older patients with advanced cancer and their caregivers share and discuss life stories together, is practical to run and if it helps. It will compare this program to usual care, which involves a social work refe…

This study is testing whether live, online group exercise classes are better than recorded videos at helping cancer survivors become more physically active. Researchers want to see if the live classes improve fitness, quality of life, and reduce feelings of loneliness. About 300 …

This study is testing a new online program called Mindset Moments to see if it's a practical and helpful way to support young cancer survivors. It aims to help 19-25 year olds who have finished their main cancer treatment but are still struggling with anxiety, depression, or dist…

This study is testing a short motivational program designed to help World Trade Center Health Program members who are cancer survivors get more physically active. Researchers will work with 84 survivors who have finished cancer treatment to see if the program increases their acti…

This study is testing a decision-making support tool designed to help older adults with acute myeloid leukemia (AML) and their caregivers. It aims to reduce emotional distress and improve the quality of shared decisions about cancer treatment. The trial will compare the new tool …

This study is testing a smartphone app designed to help children and teenagers who have had cancer. The app provides training exercises to improve long-term thinking, memory, and physical coordination problems that can occur after cancer treatment. Researchers want to see if usin…

This study is testing four different group exercise programs to see which ones best help women recover after breast cancer treatment. It will measure improvements in fitness, muscle mass, and body fat. The goal is to find the most effective workout plans to help survivors feel st…

This study is testing a new program that provides food and online cooking lessons to cancer survivors who struggle to afford healthy meals. The goal is to see if this 'Food Farmacy' approach is practical and if it helps improve people's diets, food security, and overall well-bein…

This study is testing whether a special type of play therapy can help children and teenagers with leukemia cope better during chemotherapy. Researchers will work with 66 kids, aged 10 to 18, who are receiving treatment. Over four weeks, children in the therapy group will have pla…

This study is testing whether a more comprehensive genetic test can help doctors prescribe and dose cancer medications more safely and effectively. It involves 120 adults with cancer who are already eligible for a standard genetic test related to a specific chemotherapy drug. Res…

This study aims to understand why cancer patients feel extreme fatigue and nerve pain during standard chemotherapy and radiation treatment. Researchers will observe 125 patients with various cancers, collecting blood and stool samples to look for biological markers linked to thes…

This study aims to better predict and monitor heart problems in cancer patients receiving chemotherapy. Researchers will follow 5,000 adults, using regular blood tests and heart scans to try to spot early signs of damage. The goal is to build a system that identifies patients at …

This study is testing whether adding specially trained navigators to cancer care teams helps patients. The navigators help connect patients with support services and clinical trial opportunities. Researchers will measure if this leads to better quality of life and more patients j…

This study aims to create a long-term health database for 10,000 adults who survived childhood cancer. Researchers will track participants over their lifetime to understand the long-term health effects of childhood cancer treatments. The goal is to identify risks and develop bett…

This study follows 540 cancer patients for 6 months to understand how anxiety and depression change during cancer treatment. Researchers will track patients' emotional symptoms and identify factors that might predict who needs more support. The goal is to learn how to better help…

This study is testing a new way to help teenagers and young adults with serious cancer, and their parents, have better conversations with their doctors about the future. It involves a 'communication preferences companion' who helps families figure out how they want to discuss pro…

This study aims to understand the connection between gut bacteria and two common, debilitating side effects of cancer treatment: severe fatigue and cognitive problems (often called 'chemo brain'). Researchers will enroll 250 adult cancer patients and analyze their gut bacteria wh…

This study aims to improve genetic counseling for people from all backgrounds. Researchers are testing different counseling approaches to see what creates the best patient experience. The study partners with Somali, Latino/Hispanic, Black/African American, and Hmong communities t…

This study aims to collect video and voice recordings from people with cancer to create a database for future research. Researchers want to use this data to train artificial intelligence (AI) to recognize signs of pain from facial expressions and speech patterns. The goal is to d…

This study aims to gather real-world information on how cancer patients feel and how long they live when receiving promising new treatments where the exact benefits and costs are still unclear. It will follow 100 patients, tracking their health outcomes and quality of life throug…

This study aims to learn about the experiences of cancer patients who use a mobile app called EveryDose to track their oral medication. Researchers will enroll about 25 adults who are taking oral anti-cancer drugs for the first time. The goal is to gather feedback on the app's us…

This study aims to collect detailed genetic information and health records from 25,000 adults who have cancer or are at risk of developing it. Researchers will analyze this data to better understand how cancer develops and to identify potential targets for future treatments. The …

This study aims to learn if cancer patients do better when their doctors choose treatments based on the unique genetic makeup of their tumor. Researchers will collect information from the medical records of up to 10,000 people with cancer to see how they respond to treatment and …

This study aims to see if data from wearable devices, like smartwatches, can help detect infections earlier in children receiving cancer treatment. Researchers will collect heart rate, activity, and other health data from 150 children over four weeks to train a computer model. Th…

This study aims to learn more about thymic epithelial tumors (TETs), a rare type of cancer. Researchers will collect tumor and blood samples from 50 patients undergoing surgery to analyze the immune cells and genetic features of these tumors. The goal is to build a detailed pictu…

This study aims to learn how skin conditions related to cancer or its treatment affect patients' quality of life. Over 1,000 cancer patients and survivors will fill out questionnaires about their skin-related well-being. The goal is to gather information to help improve future ca…

This study is testing whether cancer patients can safely check their own blood counts at home during chemotherapy. It aims to see if this approach reduces unnecessary trips to the hospital, saves time and money, and improves patients' quality of life. The study involves 265 patie…

This study collects tumor tissue samples from cancer patients to research whether laboratory tests can predict which patients will respond to immunotherapy drugs. Researchers will analyze how live tumor samples react to immunotherapy treatments in the lab, then compare those resu…

This study is collecting information on how adults with cancer use cannabis to manage symptoms like pain and nausea. Participants use a mobile app to track their cannabis use, symptoms, and other medications over time. The goal is to gather real-world data to help patients and do…

This study aims to understand why some people and families develop rare or multiple cancers. Researchers will observe 500 participants, including those with unusual cancers or a strong family history, to learn how genes and environmental factors work together. The study involves …

This study aims to understand why kidney disease happens, gets worse, or leads to complications like infections or heart problems. Researchers will follow 5,000 adult patients with or at risk for kidney disease for 10 years, collecting blood and urine samples. They will analyze t…

This study aims to understand what motivates or discourages older adults with cancer to stay physically active and eat well. Researchers will observe 55 participants aged 70+ to identify common motivational patterns. The goal is to use this information to design better, personali…

This study is creating a large collection of blood, tissue, and other samples from up to 10,000 cancer patients in Texas. The goal is to help scientists learn why some patients respond well to treatments like immunotherapy while others do not. By analyzing these samples alongside…

This study aims to gather information on how well different blood-thinning medications work for cancer patients who develop clots in their surface veins. Researchers will observe over 1,500 adult cancer patients with these clots to see which treatments are linked to fewer recurri…

This study is testing a program called the Clinical Trials Navigator (CTN) that helps cancer patients, their families, and doctors find suitable clinical trials across Canada, especially when trials aren't available at the patient's local hospital. It will roll out the program at…

This study aims to find markers in the blood that can predict which cancer patients will develop serious side effects from a common type of immunotherapy. Researchers will collect blood samples from 200 patients at a single hospital in France during their regular cancer check-ups…

This study is testing whether a visual digital tool can help newly diagnosed breast or head/neck cancer patients better understand their treatment options. Researchers want to see if using this tool increases overall satisfaction with the healthcare experience for patients, their…

This study aims to validate a new scoring tool designed to predict which cancer patients are most likely to develop long-term nerve pain as a result of their treatments, like surgery or chemotherapy. Researchers will enroll 625 participants, including cancer patients and healthy …

This study aims to understand if using cannabis helps or causes problems for cancer patients being treated with immunotherapy. Researchers will follow 450 patients for a year, comparing those who use cannabis to those who don't. They will track symptoms like pain, anxiety, and sl…

This study aims to create a library of blood samples from cancer patients and people at high risk for cancer. Researchers will collect these 'liquid biopsies' to help future studies develop better ways to detect cancer early and monitor treatment. The study involves 2,500 partici…

This study is testing a new artificial intelligence (AI) tool designed to help match people with advanced cancer to suitable clinical trials. It will enroll up to 50,000 patients to see if using this AI system makes it easier for patients to find and join trials. The researchers …

This study aims to learn if cancer markers found in blood samples can provide the same information as a traditional tissue biopsy. It will enroll 2,050 people already being treated for cancer to collect blood samples over time. The research is observational and will not change an…

This study aims to understand why many childhood cancer survivors continue to experience groups of symptoms like fatigue, pain, and depression. Researchers will follow 600 survivors and their caregivers, collecting surveys and stool samples over time. The goal is to see if change…

This study aims to build a large collection of blood and tissue samples from 500 cancer patients. Researchers will track specific DNA markers in the blood over time to see how they change with standard treatments. The goal is to learn if these markers can help predict how well a …

This study is testing a simple weekly survey tool to see if patients can help identify when their cancer treatment is at risk of being delayed. It aims to understand why delays happen, especially looking at differences between racial groups, to help design better support systems …

This international study aims to understand how weight loss affects body image and self-perception in people with advanced cancer. Researchers will survey 800 patients across eight countries to learn about their experiences with weight changes, appetite, and body image concerns. …

This study aims to understand how sleep problems, specifically insomnia, develop in the first year after someone is diagnosed with cancer. Researchers will follow 260 patients who had no sleep issues at diagnosis, checking in regularly to track their sleep quality, pain, mood, an…

This study aims to collect blood samples, imaging scans, and quality-of-life surveys from 5,000 cancer patients and some healthy volunteers. Researchers will track how patients respond to their cancer treatments and look for patterns in the collected data. The goal is to find bio…

This study aims to collect genetic and health information from 3,000 people to understand how genes affect medication responses. The goal is to help doctors prescribe the right drugs and doses to avoid harmful side effects, especially for people taking multiple medications. Resea…

This study is testing whether a digital system using a smartwatch and weekly surveys is a practical way to monitor the wellbeing of cancer survivors. It will involve 50 adults who have finished their main cancer treatment and have stable disease. The goal is to see if this approa…

This study aims to understand how the bacteria in our gut (the microbiome) and our diet are linked to major diseases like cancer and heart disease. It will enroll 16,000 adults over 40 to collect health information and samples over time. The goal is to build a research resource t…

This study is testing a new digital platform called the Genetics Navigator. It's designed to help guide patients and parents through the complex process of genetic testing for conditions like cancer, heart disease, and epilepsy. Researchers want to see if using this online tool r…

This study aims to understand how a person's genes affect how their immune cells respond to potential threats. Researchers will collect blood from healthy volunteers to grow immune cells in a lab and test their reactions. The goal is to learn if certain genetic patterns make peop…

This study aims to collect blood samples from people who have received or donated stem cell transplants for cancer, as well as from healthy individuals. Researchers will analyze these samples in a lab to learn how the immune system rebuilds itself after treatment. The goal is to …

This study is testing a virtual reality education tool designed to help young cancer patients and their caregivers recognize and respond to dangerous fevers during treatment. Researchers at Yale are working with 45 participants to see if this immersive VR experience is practical …

This study aims to understand what helps or hinders a positive hospital stay for Asian cancer patients. Researchers will survey 520 former patients who identify as Asian and received cancer care at MD Anderson, along with their healthcare providers. The goal is to identify specif…

This study aims to understand why some cancer patients develop autoimmune side effects when taking immunotherapy drugs called checkpoint inhibitors. Researchers will collect blood samples from 600 cancer patients before and during their immunotherapy treatment to study their immu…

This study is a registry that aims to collect information on how patients with a specific type of advanced lung cancer (NSCLC with a METex14 genetic change) are treated in real-world clinics and what their outcomes are. It will follow about 700 patients over time to understand tr…

This study is creating a large registry to collect information on how cancer is treated in real-world clinics and what the outcomes are. It will follow 20,000 adult cancer patients at participating centers, gathering data on their treatments, side effects, and results through med…

This study aims to understand how young adults with cancer feel about two different treatment spaces where they receive infusions. Researchers will survey 100 participants aged 18-39 about their satisfaction with the physical environment, staff interactions, and mental health sup…

This study aims to find the best ways to ask cancer patients about their quality of life when their disease is getting worse. Researchers will interview patients, their caregivers, and healthcare professionals to understand their preferences for how often and how these questions …

This study is testing a communication tool called TrialTalk™ to see if it helps doctors and patients talk more clearly about cancer treatment options. It involves 30 participants, including doctors and patients, who will complete surveys about their clinic visits. The goal is to …

This study aims to understand the long-term safety of gene transfer therapy by tracking the health of people who have received it. Researchers will follow up to 130 participants for 15 years, collecting health updates and blood samples to look for any delayed effects, good or bad…

This study aims to understand why some cancer patients develop serious, sometimes life-threatening, side effects from a powerful type of treatment called immune checkpoint inhibitors. Researchers will collect blood, tissue, and stool samples from 1,000 patients to look for biolog…

This study is collecting and storing tumor tissue, blood, and urine samples from cancer patients to create a resource for future research. It aims to help scientists better understand cancer by providing them with high-quality samples linked to patient health information. Partici…

This study aims to understand how cancer patients feel about stopping unnecessary medications and whether education from a pharmacist can improve their knowledge. Researchers will ask 120 Romanian cancer patients in palliative care to complete questionnaires about their attitudes…

This study aims to see if a quick, non-invasive ultrasound scan of the thigh muscle can accurately detect muscle loss in people who have finished cancer treatment. Researchers will compare the ultrasound results to standard body scans and blood tests in 55 participants. The goal …

This long-term study aims to understand what causes cancer by tracking 200,000 healthy adults aged 30-70. Participants will regularly complete health surveys, donate blood and saliva samples, and share their electronic health records over many years. Researchers will analyze this…

This study aims to understand the long-term health effects of childhood cancer treatments like chemotherapy and radiation. Researchers are following 50,000 survivors diagnosed before age 21, along with 10,000 sibling controls, to track health outcomes over many years. The goal is…

This study aims to understand advanced pancreatic cancer better by analyzing the genetic makeup of patients' tumors. Researchers will collect tumor samples and blood from about 190 patients starting chemotherapy to look for patterns in their genes. The goal is to see if these gen…

This study aims to learn how a new blood test that screens for many types of cancer works in real-world doctor's offices. Researchers will enroll 500 adults who are getting the test as part of their regular care. They will track the test's results, its financial impact, and how i…

This study aims to see if it's possible to use brain scans to understand how people with serious illnesses like cancer, COPD, or heart failure experience chronic breathlessness. Researchers will use functional MRI scans and immersive virtual reality with 16 participants to see if…

This study aims to build a large database and sample collection to research why some groups face more barriers to cancer screening and early detection. It will enroll 100,000 adults, focusing on underserved communities, to collect health information and biological samples over te…

This is a very early study to check if a new drug called LY4066708 is safe for people and to see how the body handles it. It will involve about 104 healthy volunteers who will receive the drug and be monitored for up to 24 weeks. The main goals are to identify any side effects an…

This study aims to determine if a more detailed genetic analysis of tumors helps doctors choose better treatments for cancer patients. It will compare a standard genetic test with a more complex one in nearly 8,000 adults with advanced cancer who are starting their first treatmen…

This study aims to see if getting expert advice on a patient's unique tumor genetics helps doctors make better treatment decisions. Researchers will analyze the tumor genes of about 192 cancer patients and have a special panel of experts recommend treatments. They will then track…

This study aims to create better formulas for measuring how the human body uses energy (metabolism). Researchers will compare 2000 healthy volunteers and people with conditions like diabetes or cancer. They will use detailed scans and breath tests during short hospital stays to u…

This study looks at whether exercise after cancer treatment affects how long survivors stay cancer-free and their overall survival. Researchers will analyze existing health records from 1,000 adult cancer survivors who completed treatment at least 3 months ago. The goal is to und…

This study aims to collect genetic samples and information from cancer patients to build a research library, or biobank. Researchers will analyze DNA from blood and tumor tissue to look for genetic markers that could help understand what causes cancer. The goal is to use this inf…

This study aims to understand why some cancer patients have difficulty accessing clinical trials and research opportunities. Researchers will survey 300 cancer patients in Cheshire and Merseyside to identify barriers like socioeconomic status, ethnicity, and practical challenges.…

This study aims to understand if the types of bacteria in a patient's gut influence whether they get diarrhea from certain cancer drugs. Researchers will follow 150 patients starting cancer treatment, collecting stool and blood samples to analyze their gut bacteria and inflammati…

This study is testing new outreach and education strategies to increase enrollment of Black and Hispanic patients in cancer treatment trials at Moffitt Cancer Center. Researchers will work with community members, doctors, and patients using educational sessions, digital tools, an…

This study is testing a new imaging agent called 68Ga-NYM096 to see how well it shows up in different types of cancer on PET/CT scans. It will involve 120 adult patients with confirmed cancer who will receive one injection of the tracer followed by a full-body scan. The goal is t…

This study aims to gather real-world information from 5,500 Canadian adults with cancer who have uncommon genetic changes in their tumors. It will track their health journeys, treatments, and quality of life to understand how different therapies work for these specific genetic pr…

This study is testing a support program designed to help more Black and Latino cancer patients join clinical trials. It will provide patients with trial navigators and educational tools at community cancer clinics. The goal is to understand what helps patients from underrepresent…

This study is looking for a better way to predict which cancer patients might have serious bleeding while taking blood thinners for a clot. Researchers will measure a specific blood test (thrombin generation) in 212 patients with cancer and a recent blood clot. They will see if t…

This study is testing different outreach methods to see which ones work best to increase enrollment of African American patients in early-phase cancer treatment trials. It will enroll both patients and their doctors to receive different recruitment approaches or no special outrea…

This study aims to understand how well different fertility preservation methods work for people whose medical treatments (like cancer therapy) might affect their future ability to have children. Researchers will review the medical records of up to 100 patients who have used these…

This study aims to see how well new blood and urine tests can find cancer early in firefighters, who face higher cancer risks from their job. Researchers will enroll 2,000 currently employed firefighters to donate samples and track their health over time. The main goal is to meas…

This study aims to understand how Black and White patients with solid tumor cancer use cannabis, opioids, and tobacco to manage their pain and symptoms. Researchers will follow 600 participants for 12 months, using a smartphone app to collect real-time data on their daily experie…

This study aims to understand why cancer patients who report needs like transportation, food, or housing problems choose not to accept help when it's offered. Researchers will survey 500 patients and interview some to learn about barriers like mistrust, feeling others need help m…

This study is exploring whether patients are interested in using telehealth and digital tools for cancer genetic counseling and testing. Researchers want to see if these remote options work as well as traditional in-person visits. The study involves 360 adults who meet guidelines…

This study aims to learn more about how COVID-19 affects children and young adults, particularly those with cancer. Researchers will collect samples from participants who have tested positive for the virus to understand their symptoms, how their immune system responds, and how lo…

This study aims to collect tumor tissue and blood cells from people with advanced solid tumors to prepare for future CAR T-cell therapy. Researchers will analyze the cancer tissue to understand how tumors hide from the immune system and collect participants' own immune cells thro…

This study aims to understand how the community of bacteria in a person's gut (the microbiome) might affect how well their cancer responds to immunotherapy drugs. Researchers will compare the gut bacteria of patients whose cancer got worse during treatment to those who were stabl…

This study aims to better understand the different types and causes of fatigue, which is a common symptom in many conditions like cancer, lupus, and chronic fatigue syndrome. Researchers will enroll about 700 adults, both with and without fatigue, to complete questionnaires, phys…

This study aims to find out if cancer patients have better health outcomes when they visit the emergency department at their specialized cancer hospital compared to a general hospital. Researchers will track 2,000 adults with active or recent cancer who need emergency care. The g…

This study is a survey for adults who have received CAR-T cell therapy for cancer. Researchers want to understand how this treatment might affect a patient's ability to have children. The information collected will help doctors better advise future patients about fertility risks …

This study aims to identify blood markers that can predict whether cancer patients will respond to FDA-approved immunotherapy treatments. Researchers will follow 1,500 patients receiving treatments like pembrolizumab or nivolumab, tracking their response over six months. The goal…

This study is creating a large registry of people interested in research on inherited cancer risk. It aims to gather health information from up to 10,000 adults to help scientists better understand how genetics influence cancer. Participants complete surveys and may be invited to…

This study compares online genetic counseling to traditional in-person visits for people getting tested for inherited cancer risks. Researchers want to see if a self-guided website works as well as meeting with a genetic counselor for helping people understand their results and m…

This study aims to understand what cancer doctors, patients, and their family caregivers think about the idea of receiving hospital-level cancer care at home. Researchers will conduct interviews and focus groups to gather opinions and identify potential challenges. The goal is to…

This study aims to understand how common muscle weakness and cognitive problems (often called 'chemobrain') are in people who have finished cancer treatment. Researchers will collect health data from 100 adult cancer survivors during a standard follow-up check-up day. The goal is…

This study aims to understand how cancer survivors experience and talk about the fatigue that often lingers after treatment. Researchers will interview 80 survivors and their doctors to learn the words and descriptions they use. The goal is to create a visual poster to help patie…

This early research study aims to understand if changing people's automatic, gut-feeling attitudes toward physical activity can help them exercise more consistently. The study will involve 120 inactive adults who are overweight or obese, using smartphone prompts and Fitbit tracke…

This study aims to collect real-world information on how patients with rare cancers or rare genetic changes in their cancer fare when using approved targeted therapies. It will track survival, quality of life, and how well the treatment works. The goal is to gather strong evidenc…

This study aims to understand the long-term health effects and disease progression in people who have received radiation therapy for cancer. Researchers will collect follow-up health data from 700 adult participants who previously had radiation treatment. The goal is to learn abo…

This study is testing an education program called CTNow, designed to help cancer patients and their doctors in rural Hawaii learn more about clinical trials. The goal is to make it easier for patients to find out about and get referred to cancer research studies. The program uses…

This study aims to discover new genes that make people more likely to get cancer, especially when it runs in families. Researchers are enrolling 1,500 adults and children who either have cancer themselves or have a family history suggesting inherited risk. By analyzing participan…

This study is building a large collection of tissue samples and health information from people to help researchers develop better ways to detect and treat cancer. It aims to enroll 100,000 adults who can provide consent. The goal is to create a shared resource for scientists to s…

This study is testing a new questionnaire designed to help women with metastatic breast cancer and their caregivers talk about their personal values and goals with their doctors. The goal is to see if using this tool helps patients feel less conflicted about decisions and improve…