Glow-in-the-Dark dye could help surgeons spot hidden cancer

NCT ID NCT07538648

Recruiting now Diagnosis Sponsor: Zhejiang Cancer Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial is testing an injectable dye called NC527-X that may make tumors glow during surgery, helping surgeons see exactly where the cancer is. The study will enroll 400 adults with solid tumors who are already scheduled for surgery. Participants receive one of four different doses of the dye before their operation, and researchers measure how well the dye highlights the tumor compared to healthy tissue.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: NC527-X (an injectable imaging agent)
What this could lead to: If successful, this could give surgeons a real-time way to see tumor edges during surgery, potentially leading to more complete tumor removal.
What could go wrong: This is an early Phase 1 trial with small dose groups, so it is mainly testing safety and the right dose. The imaging agent may not work well for all tumor types.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CANCER

Contacts and locations

Locations

Zhejiang Cancer Hospital
RECRUITING

Hangzhou, Zhejiang, 310000, China

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