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Spinal pain pump may offer relief for cancer patients when opioids fail

NCT ID NCT07691840

Recruiting now Symptom relief Sponsor: Universitair Ziekenhuis Brussel Source: ClinicalTrials.gov ↗

First seen Jul 09, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This trial tests whether a small pump implanted in the abdomen that delivers pain medicine directly to the spinal fluid can improve quality of life for people with severe cancer pain that is not controlled by oral opioids. Participants are randomly assigned to get the pump or to continue with standard oral pain medications. The study measures quality of life, comfort, and survival over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Intrathecal drug delivery system (implanted pump delivering morphine and/or local anesthetics into spinal fluid)
What this could lead to
If it works, this could offer a more effective way to manage severe cancer pain with fewer side effects than high-dose oral opioids.
What could go wrong
This is a moderate-sized trial, and the pump implant is a surgical procedure with risks like infection or device malfunction. It may not improve quality of life more than standard care.

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Conditions

The condition(s) this trial relates to.

cancer Cancer Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CONVENTIONAL MEDICAL MANAGEMENT INTRATHECAL DRUG DELIVERY REFRACTORY CANCER PAIN

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UZ Brussel

    RECRUITING

    Jette, 1090, Belgium

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

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