Universitair Ziekenhuis Brussel

This study is testing if giving a single dose of the immunotherapy drug pembrolizumab six weeks before surgery can help the body's immune system attack high-risk melanoma cells that might be too small to see on scans. It involves 49 adults with high-risk melanoma that hasn't visi…

This study is testing whether a hydrogen/methane breath test can predict if people with moderate to severe Irritable Bowel Syndrome (IBS) will get better on a lactose-free diet. Researchers will enroll 90 IBS patients to see if the test results match their symptom improvement and…

This study is testing a minimally invasive procedure called Superior Rectal Artery Embolization (SRAE) for people with bleeding hemorrhoids. Researchers want to see if blocking the blood supply to the hemorrhoids works as well as two common treatments (rubber band ligation and DG…

This study is testing a new, faster type of CT scan to quickly check for blocked heart arteries in people who have survived a cardiac arrest. The goal is to see if this scan is as accurate as the current, more complex test (coronary angiography) at finding blockages. If it works,…

This study is testing a new, faster type of CT scan for people who come to the emergency room with chest pain and high troponin levels (a sign of possible heart injury). The new scan doesn't require an electrocardiogram (ECG) and can check the heart, lungs, and major blood vessel…

This study is testing whether regular cardiovascular exercise can help reduce symptoms for people with Irritable Bowel Syndrome (IBS) who have a sedentary lifestyle. Researchers will work with 30 adults with moderate IBS symptoms to see if a supervised exercise program improves t…

This study is testing whether a daily probiotic supplement can help prevent excessive crying and colic in healthy newborns. Researchers will give either the probiotic or a placebo to 768 infants during their first 3 months of life. The study will measure crying time, colic occurr…

This study is testing if a low FODMAP diet can improve symptoms and quality of life for people with moderate to severe Irritable Bowel Syndrome (IBS), specifically in those who do not have trouble digesting lactose. It will involve 60 participants who will follow the diet for 4 w…

This study aims to understand anal cancer risk in men who have sex with men (MSM) who take medication to prevent HIV. Researchers want to know how common precancerous changes are in this group and test different screening methods to detect them early. The study will also measure …

This study aims to find out if a wearable continuous glucose monitor (CGM) can predict when someone at high risk for Type 1 diabetes will actually develop the disease. Researchers will follow 75 children and adults (ages 5-39) who have markers for diabetes but no symptoms, for 2-…

This study aims to test how reliable a new food questionnaire is for tracking what people eat, including FODMAPs. Researchers will compare the questionnaire to a standard 4-day food diary in 400 participants, including people with and without IBS. They will also look for connecti…

This study is testing whether an artificial intelligence (AI) tool can rank embryos for IVF as effectively as a trained embryologist. About 1,325 women undergoing IVF will have their frozen embryos ranked either by the AI or by an embryologist. The main goal is to see if both met…

This study aims to find out if a newer, simpler breathing test called impulse oscillometry (IOS) provides useful information for monitoring asthma. Researchers will follow 50 adult asthma patients for 3 to 6 months after their medication is changed. They will compare results from…

This study aims to better understand why some people experience fecal incontinence (loss of bowel control) while others experience double incontinence (loss of both bowel and bladder control). Researchers will enroll 150 adults with these conditions to compare their medical histo…

This study is trying to understand if the recipe of the fluid used in dialysis machines affects blood inflammation and clotting. It will involve 15 patients already in a related trial. Researchers will test three different fluid recipes and collect blood samples to see how white …

This study aims to understand if babies are born with 'self-attacking' antibodies that target their own skin cells, and if these antibodies are linked to developing eczema. Researchers will follow 500 newborns, some at high risk for eczema, for two years. They will check umbilica…

This study is testing a new tool called SWEET that predicts how long a specific medical procedure (ERCP) will take. Researchers want to see if this tool is more accurate than a doctor's best guess. The goal is to help hospitals schedule procedures better, reduce wait times, and i…

This study aims to better understand how COPD changes over time. Researchers will follow 100 adults with COPD for one year, checking their breath and a small blood sample every six months. The goal is to see if certain markers in the breath or blood are different in people whose …

This study aims to understand how well patients recovering from a serious ICU stay absorb nutrients when fed through a tube. Researchers will measure the energy in patients' stool and their body's energy use to see how much nutrition from the feeding is actually absorbed. The goa…

This study aims to understand if there are physical differences in body composition between women with functional dyspepsia (chronic unexplained stomach discomfort) and healthy women. Researchers will use a painless electrical scan to measure body fat, muscle mass, and other phys…