One shot before surgery: could early immunotherapy stop melanoma in its tracks?

NCT ID NCT07448831

First seen Mar 23, 2026 · Last updated Jun 17, 2026 · Updated 14 times

Summary

This study is testing whether giving one dose of the immunotherapy drug pembrolizumab six weeks before surgery can help the immune system fight high-risk melanoma more effectively. About 49 adults with melanoma that hasn't spread on scans will receive the drug, then have their lymph nodes checked during surgery. Afterward, some will continue standard immunotherapy for a year, and all are monitored for five years to see if the early treatment reduces the chance of the cancer coming back.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • UZ Brussel

    RECRUITING

    Jette, Brussels Capital, 1090, Belgium

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.

Conditions inferred from the trial description

These were inferred from the trial's summary, not listed by the trial registrant.