Can a low FODMAP diet soothe IBS even without lactose issues?
NCT ID NCT05120752
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 3 trial tests whether a low FODMAP diet can improve symptoms and quality of life in people with moderate to severe irritable bowel syndrome (IBS) who do not have lactose malabsorption. Sixty participants will follow the diet with guidance from a dietitian. The goal is to see if this restrictive diet still helps when lactose digestion is normal.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
low FODMAP diet
What this could lead to
If successful, this could show that a low FODMAP diet helps ease IBS symptoms even in people without lactose issues, offering a clear dietary option.
What could go wrong
This is a small, early-phase trial with only 60 people. It may not prove effective for everyone, and the restrictive diet can be hard to follow.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UZ Brussel
RECRUITINGJette, Brussels Capital, 1090, Belgium
Contact