Gut bacteria during infection may flag IBS risk

NCT ID NCT03223077

First seen Aug 07, 2026 ยท Last updated Aug 07, 2026

Summary

This study looks at how a Campylobacter gut infection changes the bacteria and lining of the bowel, and whether these changes can help identify who might later develop irritable bowel syndrome (IBS). Researchers will follow people with a confirmed Campylobacter infection who do not have a history of IBS or other bowel diseases. The goal is to see if certain gut changes during the acute infection are linked to the development of IBS afterward.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could help identify people at higher risk for developing IBS after a gut infection, potentially leading to early interventions or preventive strategies.
What could go wrong
This is an observational study, so it cannot prove cause and effect. The findings may not apply to all populations, and the link between gut bacteria and IBS risk may be complex and influenced by many factors.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55902, United States

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