Wheat sensitivity linked to fatty liver? a new study investigates

NCT ID NCT07750535

Recruiting now Knowledge-focused Sponsor: University of Palermo Source: ClinicalTrials.gov ↗

First seen Aug 06, 2026 · Last updated Aug 12, 2026 · Updated 3 times

Summary

This study looks at whether people with non-celiac wheat sensitivity (NCWS) have a higher chance of having fatty liver or liver scarring. Researchers will compare liver health in people with NCWS to those with irritable bowel syndrome, functional dyspepsia, and celiac disease. They will use ultrasound and FibroScan to measure liver fat and stiffness, along with blood-based scores. The goal is to see if wheat sensitivity is linked to liver problems and if avoiding wheat might protect the liver.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If the link is confirmed, it could lead to better screening for liver problems in people with wheat sensitivity and possibly dietary guidance to protect the liver.
What could go wrong: This is an observational study, so it can only show associations, not cause and effect. The results may not apply to everyone, and the findings need confirmation in larger, more diverse groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

celiac disease dyspepsia functional gastric disease irritable bowel syndrome metabolic dysfunction-associated steatotic liver disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CELIAC DISEASE FUNCTIONAL DYSPEPSIA IRRITABLE BOWEL SYNDROME METABOLIC DYSFUNCTION-ASSOCIATED STEATOTIC LIVER DISEASE NON CELIAC WHEAT SENSITIVITY

Contacts and locations

Locations

Internal Medicine Unit, "Villa-Sofia-Cervello" Hospital
RECRUITING

Palermo, Palermo, 90146, Italy
Internal Medicine Unit, University Hospital of Palermo
RECRUITING

Palermo, Palermo, 90127, Italy

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