FUNCTIONAL DYSPEPSIA

This study tests if stimulating specific points on the ear can improve stomach discomfort and sleep in people with functional dyspepsia (chronic indigestion) and insomnia. Researchers will enroll 176 adults and compare the ear stimulation to a placebo. The goal is to see if this …

This study tests whether a probiotic called Clostridium butyricum can improve anxiety and depression in people with functional dyspepsia, a common stomach disorder. About 180 adults will receive either the probiotic or a placebo for 4 weeks, alongside standard stomach medication.…

This study tests whether two medications, amitriptyline and trifluoperazine, can reduce stomach symptoms like pain, fullness, and burning in people with functional dyspepsia. About 120 adults will take one of the drugs or standard treatment for 8 weeks, then be followed for 4 mor…

This study tests two digital treatments for children aged 8-17 with long-lasting stomach pain caused by gut-brain interaction issues. After a short online education program, participants are randomly assigned to either internet-based cognitive behavioral therapy (iCBT) or gut-dir…

This study tests a non-invasive device that stimulates a nerve in the ear, combined with support therapy, to help people with functional dyspepsia (chronic stomach pain and discomfort). The goal is to reduce gut-related anxiety and improve digestion. 80 adults aged 18-65 will par…

This study tests whether a natural extract called EDL (from the Dolichos lablab plant) can reduce stomach discomfort in adults with functional dyspepsia—a condition where the stomach feels upset without a clear medical cause. About 100 participants will take EDL or a placebo dail…

This study tests whether ketotifen, a drug that stabilizes certain immune cells, can reduce stomach pain in children aged 8-17 with functional dyspepsia (chronic indigestion) linked to high levels of eosinophils in the gut. Participants will receive both ketotifen and a placebo a…

This study is for children aged 11-18 with conditions like cyclic vomiting or functional dyspepsia, where the gut and brain don't communicate properly. Researchers will use a special tracking software to measure nerve activity and then give a personalized, non-invasive ear stimul…

This study tests a daily supplement containing two types of probiotics and ginger extract in 198 adults with functional dyspepsia, a condition causing stomach pain, fullness, and burning. Participants take one capsule daily for 8 weeks to see if it reduces symptoms and improves q…

This study tests whether using virtual reality can reduce stomach pain and other digestive symptoms in people with functional dyspepsia. About 30 adults with this condition will try VR sessions and report their symptom changes. The goal is to see if VR offers a safe, drug-free wa…

This study looks at whether a yoga program is practical and helpful for people with functional dyspepsia or gastroparesis, conditions that cause nausea and vomiting. Ten adults will try the yoga sessions and report how they feel. The goal is to see if yoga can be a useful tool to…

This study looks at whether using press needles (small needles taped to the skin) on body and ear acupuncture points, along with regular medication, can reduce symptoms and improve quality of life for people with functional dyspepsia (stomach discomfort without a clear cause). Ab…

This study tests a type of talking therapy (exposure-based CBT) for adults who have both functional dyspepsia (stomach pain or fullness after eating) and avoidant/restrictive food intake disorder (ARFID) with weight loss. The goal is to see if the therapy helps people eat more co…

This study tests whether a probiotic called Bacillus coagulans can reduce anxiety and depression in people with functional dyspepsia (a condition causing stomach pain and discomfort without a clear cause). The trial will include 180 adults aged 18-80 who have mild to moderate anx…

This study compares body composition—like fat and muscle mass—between women with functional dyspepsia (a condition causing stomach pain and discomfort without a clear cause) and healthy women. Researchers will use a simple, non-invasive device called bio-electrical impedance anal…

This study looks at whether people with a certain type of stomach lining damage (chronic atrophic gastritis) have different indigestion symptoms than those without it. About 315 adults who recently had an upper endoscopy will answer questionnaires and provide blood samples. The g…

This study aims to find out how common non-celiac wheat sensitivity (NCWS) and other gut issues like irritable bowel syndrome (IBS) are among relatives of people with celiac disease. Researchers will ask 600 adult relatives to follow a wheat-free diet for 6 weeks and report their…