FUNCTIONAL DYSPEPSIA

This study is testing a personalized approach to help children with chronic nausea, vomiting, and related symptoms like dizziness and fatigue. Researchers will use a new software to measure a child's nervous system activity in real-time and adjust a gentle ear-based nerve stimula…

This study is testing if a medication called ketotifen can help children and teenagers who have ongoing stomach pain (functional dyspepsia) linked to high levels of certain immune cells in their gut. Participants will try both ketotifen and a placebo pill in a random order to see…

This study is testing a special type of talk therapy for adults who have chronic stomach pain (functional dyspepsia) and, as a result, avoid eating certain foods and have lost weight. The therapy uses gentle, repeated exposure to feared foods to help people eat more comfortably. …

This study is testing whether two existing medications, amitriptyline and trifluoperazine, can help reduce symptoms of functional dyspepsia (chronic stomach discomfort). Researchers will compare these drugs against standard treatment in 120 adults over 12 weeks. The main goal is …

This study is testing whether using virtual reality (VR) can help reduce stomach pain and other digestive symptoms in people with functional dyspepsia. Researchers at Mayo Clinic will have 30 participants use VR to see if it eases symptoms like abdominal pain, nausea, bloating, a…

This study is testing whether a specific probiotic (Clostridium butyricum) can help reduce feelings of anxiety and depression in people who have functional dyspepsia, a common condition causing ongoing stomach pain or discomfort. The trial will involve 180 adults who will take ei…

This study is testing whether combining two approaches—a gentle ear stimulation device and weekly video therapy sessions—can help people with functional dyspepsia. Researchers want to see if this 'gut-brain' approach reduces stomach pain, bloating, and anxiety related to digestio…

This study is testing two online psychological treatments to help children and teenagers manage chronic stomach pain caused by gut-brain communication problems. Researchers are comparing internet-based cognitive behavioral therapy (iCBT) with gut-directed hypnotherapy delivered t…

This study is testing whether a specific probiotic supplement (Bacillus coagulans) can help reduce feelings of anxiety and depression in people who also have chronic stomach discomfort (functional dyspepsia). About 180 adults will take either the probiotic or a placebo (dummy pil…

This study is testing if a seated yoga program is a practical and acceptable way to help manage nausea and vomiting for people with functional dyspepsia or gastroparesis. Researchers are adapting a yoga program originally designed for cancer patients to see if it works for these …

This study is testing if a non-drug therapy using gentle pressure on specific points of the ear can help people who have both chronic stomach discomfort (functional dyspepsia) and trouble sleeping. Researchers will enroll 176 participants to see if this approach safely reduces sy…

This study is testing whether a daily dietary supplement containing specific probiotics and ginger extract can help reduce stomach pain, fullness, and discomfort in adults with functional dyspepsia. About 200 participants will take one capsule daily for 8 weeks to see if it impro…

This study is testing whether a type of acupuncture using small press needles can help people with functional dyspepsia, a condition causing ongoing stomach pain, bloating, and fullness without a clear cause. Researchers are comparing real press needles to fake ones to see if the…

This study aims to understand if people with a specific type of confirmed stomach lining damage (chronic atrophic gastritis) experience different or worse digestive symptoms than those without it. Researchers will observe about 315 adults who have had a recent stomach scope showi…

This study aims to understand if there are physical differences in body composition between women with functional dyspepsia (chronic unexplained stomach discomfort) and healthy women. Researchers will use a painless electrical scan to measure body fat, muscle mass, and other phys…