Could old drugs ease mysterious stomach pain?

NCT ID NCT07008235

Recruiting now Symptom relief Sponsor: Md. Moktadirul Hoque Shuvo Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether two medications, amitriptyline and trifluoperazine, can reduce stomach symptoms in people with functional dyspepsia—a condition where the stomach feels upset without a clear cause. About 120 adults will take one of the drugs or stick with standard treatment for 8 weeks, then be monitored for 4 more weeks. Researchers will track symptom changes and any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: amitriptyline and trifluoperazine
What this could lead to: If successful, this could point toward a new treatment option for people with functional dyspepsia who don't get enough relief from standard care.
What could go wrong: This is a mid-stage trial with only 120 participants, so results may not apply to everyone. Both drugs can cause side effects like drowsiness or dizziness.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dyspepsia functional gastric disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

FUNCTIONAL DYSPEPSIA

Contacts and locations

Locations

Dhaka Medical College
RECRUITING

Dhaka, 1000, Bangladesh

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