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Can therapy help you eat again when your stomach hurts?

NCT ID NCT05587127

Recruiting now Symptom relief Sponsor: Massachusetts General Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a type of talking therapy called exposure-based cognitive behavioral therapy (CBT) for adults who have both functional dyspepsia (a stomach condition causing pain and fullness) and avoidant/restrictive food intake disorder (ARFID), leading to weight loss. Fifty participants will receive eight weekly therapy sessions online or continue usual care. The goal is to see if the therapy helps them eat more variety and volume, improve symptoms, and gain weight.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
cognitive behavioral therapy (CBT)
What this could lead to
If it works, this could offer a structured therapy to help people with functional dyspepsia overcome food avoidance and regain weight.
What could go wrong
This is a small, early-stage trial with only 50 participants, so results may not apply widely. The therapy requires weekly sessions and may not work for everyone.

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Conditions

The condition(s) this trial relates to.

avoidant/restrictive food intake disorder dyspepsia eating disorder Feeding and Eating Disorders functional gastric disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

APPETITE REGULATION AVOIDANT RESTRICTIVE FOOD INTAKE DISORDER BEHAVIORAL MEDICINE COGNITIVE BEHAVIORAL THERAPY DYSPEPSIA FEEDING AND EATING DISORDERS FUNCTIONAL DYSPEPSIA POST PRANDIAL DISTRESS SYNDROME

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Massachusetts General Hospital

    RECRUITING

    Boston, Massachusetts, 02114, United States

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

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