Gut feeling: probiotic shows promise for mood in stomach disorder

NCT ID NCT07187492

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a probiotic called Bacillus coagulans can reduce anxiety and depression in people with functional dyspepsia, a common stomach disorder. 180 adults will receive either the probiotic or a placebo for 4 weeks, alongside standard treatment. The main goal is to see if mood scores improve, with secondary measures looking at overall stomach symptoms and sleep quality.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Bacillus coagulans (a probiotic)

What this could lead to

If it works, this could offer a simple, natural way to improve mood and stomach symptoms in people with functional dyspepsia.

What could go wrong

This is a small, early-phase trial. The effect may be small or no better than placebo, and results may not apply to everyone with these conditions.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder Depression depressive disorder dyspepsia functional gastric disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Air Force Medical University

    RECRUITING

    Xi’an, Shanxi, China