Gut feeling: probiotic shows promise for mood in stomach disorder

NCT ID NCT07187492

Recruiting now Symptom relief Sponsor: Xijing Hospital of Digestive Diseases Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a probiotic called Bacillus coagulans can reduce anxiety and depression in people with functional dyspepsia, a common stomach disorder. 180 adults will receive either the probiotic or a placebo for 4 weeks, alongside standard treatment. The main goal is to see if mood scores improve, with secondary measures looking at overall stomach symptoms and sleep quality.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Bacillus coagulans (a probiotic)
What this could lead to: If it works, this could offer a simple, natural way to improve mood and stomach symptoms in people with functional dyspepsia.
What could go wrong: This is a small, early-phase trial. The effect may be small or no better than placebo, and results may not apply to everyone with these conditions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder Depression depressive disorder dyspepsia functional gastric disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANXIETY DEPRESSION FUNCTIONAL DYSPEPSIA PROBIOTICS

Contacts and locations

Locations

Air Force Medical University
RECRUITING

Xi’an, Shanxi, China

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